Lipotoxicity, β cell dysfunction, and gestational diabetes

Christopher J. Nolan

doi:10.1016/j.cmet.2014.03.020

Lipotoxicity, β cell dysfunction, and gestational diabetes

Christopher J. Nolan^*

^*Corresponding author for this work

Research output: Contribution to journal › Short survey › peer-review

22 Citations (Scopus)

Abstract

Gestational diabetes (GDM) is caused by failure of islet β cells to meet the increased insulin requirements of pregnancy. Recently, Prentice et al. (2014) discovered a 7-fold elevation of the furan fatty acid metabolite 3-carboxy-4-methyl-5-propyl-2-furanopropanoic acid (CMPF) in plasma of women with GDM and showed that CMPF directly induces β cell dysfunction.

Original language	English
Pages (from-to)	553-554
Number of pages	2
Journal	Cell Metabolism
Volume	19
Issue number	4
DOIs	https://doi.org/10.1016/j.cmet.2014.03.020
Publication status	Published - 1 Apr 2014

Access to Document

10.1016/j.cmet.2014.03.020

Cite this

@article{5c275169a8fb47d7b172b51cb0298b52,

title = "Lipotoxicity, β cell dysfunction, and gestational diabetes",

abstract = "Gestational diabetes (GDM) is caused by failure of islet β cells to meet the increased insulin requirements of pregnancy. Recently, Prentice et al. (2014) discovered a 7-fold elevation of the furan fatty acid metabolite 3-carboxy-4-methyl-5-propyl-2-furanopropanoic acid (CMPF) in plasma of women with GDM and showed that CMPF directly induces β cell dysfunction.",

author = "Nolan, \{Christopher J.\}",

year = "2014",

month = apr,

day = "1",

doi = "10.1016/j.cmet.2014.03.020",

language = "English",

volume = "19",

pages = "553--554",

journal = "Cell Metabolism",

issn = "1550-4131",

publisher = "Cell Press",

number = "4",

}

TY - JOUR

T1 - Lipotoxicity, β cell dysfunction, and gestational diabetes

AU - Nolan, Christopher J.

PY - 2014/4/1

Y1 - 2014/4/1

N2 - Gestational diabetes (GDM) is caused by failure of islet β cells to meet the increased insulin requirements of pregnancy. Recently, Prentice et al. (2014) discovered a 7-fold elevation of the furan fatty acid metabolite 3-carboxy-4-methyl-5-propyl-2-furanopropanoic acid (CMPF) in plasma of women with GDM and showed that CMPF directly induces β cell dysfunction.

AB - Gestational diabetes (GDM) is caused by failure of islet β cells to meet the increased insulin requirements of pregnancy. Recently, Prentice et al. (2014) discovered a 7-fold elevation of the furan fatty acid metabolite 3-carboxy-4-methyl-5-propyl-2-furanopropanoic acid (CMPF) in plasma of women with GDM and showed that CMPF directly induces β cell dysfunction.

UR - https://www.scopus.com/pages/publications/84897518893

U2 - 10.1016/j.cmet.2014.03.020

DO - 10.1016/j.cmet.2014.03.020

M3 - Short survey

SN - 1550-4131

VL - 19

SP - 553

EP - 554

JO - Cell Metabolism

JF - Cell Metabolism

IS - 4

ER -

Lipotoxicity, β cell dysfunction, and gestational diabetes

Abstract

Access to Document

Other files and links

Fingerprint

Cite this