Localisation of a candidate anion transporter to the surface of the malaria parasite

Roselani I. Henry; Rowena E. Martin; Susan M. Howitt; Kiaran Kirk

doi:10.1016/j.bbrc.2007.08.116

Localisation of a candidate anion transporter to the surface of the malaria parasite

Roselani I. Henry
, Rowena E. Martin
, Susan M. Howitt
, Kiaran Kirk^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

8 Citations (Scopus)

Abstract

PfSulP, encoded by the human malaria parasite Plasmodium falciparum, is a member of the sulphate permease family of anion transporter proteins. By transfecting the parasite with an epitope-tagged version of PfSulP, and detecting via western blot and indirect immunofluorescent assay microscopy, we show that PfSulP is localised to the surface of the intraerythrocytic parasite, where it is postulated to play a role in the flux of anions across the parasite plasma membrane.

Original language	English
Pages (from-to)	288-291
Number of pages	4
Journal	Biochemical and Biophysical Research Communications
Volume	363
Issue number	2
DOIs	https://doi.org/10.1016/j.bbrc.2007.08.116
Publication status	Published - 16 Nov 2007

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10.1016/j.bbrc.2007.08.116

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title = "Localisation of a candidate anion transporter to the surface of the malaria parasite",

abstract = "PfSulP, encoded by the human malaria parasite Plasmodium falciparum, is a member of the sulphate permease family of anion transporter proteins. By transfecting the parasite with an epitope-tagged version of PfSulP, and detecting via western blot and indirect immunofluorescent assay microscopy, we show that PfSulP is localised to the surface of the intraerythrocytic parasite, where it is postulated to play a role in the flux of anions across the parasite plasma membrane.",

keywords = "Anion, Chloride, Membrane, Permease, Plasmodium falciparum, SulP, Sulphate, Transporter",

author = "Henry, \{Roselani I.\} and Martin, \{Rowena E.\} and Howitt, \{Susan M.\} and Kiaran Kirk",

year = "2007",

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doi = "10.1016/j.bbrc.2007.08.116",

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T1 - Localisation of a candidate anion transporter to the surface of the malaria parasite

AU - Henry, Roselani I.

AU - Martin, Rowena E.

AU - Howitt, Susan M.

AU - Kirk, Kiaran

PY - 2007/11/16

Y1 - 2007/11/16

N2 - PfSulP, encoded by the human malaria parasite Plasmodium falciparum, is a member of the sulphate permease family of anion transporter proteins. By transfecting the parasite with an epitope-tagged version of PfSulP, and detecting via western blot and indirect immunofluorescent assay microscopy, we show that PfSulP is localised to the surface of the intraerythrocytic parasite, where it is postulated to play a role in the flux of anions across the parasite plasma membrane.

AB - PfSulP, encoded by the human malaria parasite Plasmodium falciparum, is a member of the sulphate permease family of anion transporter proteins. By transfecting the parasite with an epitope-tagged version of PfSulP, and detecting via western blot and indirect immunofluorescent assay microscopy, we show that PfSulP is localised to the surface of the intraerythrocytic parasite, where it is postulated to play a role in the flux of anions across the parasite plasma membrane.

KW - Anion

KW - Chloride

KW - Membrane

KW - Permease

KW - Plasmodium falciparum

KW - SulP

KW - Sulphate

KW - Transporter

UR - https://www.scopus.com/pages/publications/34748836373

U2 - 10.1016/j.bbrc.2007.08.116

DO - 10.1016/j.bbrc.2007.08.116

M3 - Article

SN - 0006-291X

VL - 363

SP - 288

EP - 291

JO - Biochemical and Biophysical Research Communications

JF - Biochemical and Biophysical Research Communications

IS - 2

ER -

Localisation of a candidate anion transporter to the surface of the malaria parasite

Abstract

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