Magnetizing DNA and proteins using responsive surfactants

Paul Brown; Asad M. Khan; James P.K. Armstrong; Adam W. Perriman; Craig P. Butts; Julian Eastoe

doi:10.1002/adma.201202685

Magnetizing DNA and proteins using responsive surfactants

Paul Brown, Asad M. Khan, James P.K. Armstrong, Adam W. Perriman, Craig P. Butts, Julian Eastoe^*

^*Corresponding author for this work

Research School of Chemistry

Research output: Contribution to journal › Article › peer-review

77 Citations (Scopus)

Abstract

DNA chains and their movement in solvent may now be controlled simply by surfactant binding and the switching "on" and "off" of a magnetic field adding a new paradigm to the study and control, condensation and manipulation of DNA (and other biomolecules). Such control is essential for biotechnological applications such as transfection and the regulation of gene suppression, as well as in materials science concerning soft molecular self-assemblies.

Original language	English
Pages (from-to)	6244-6247
Number of pages	4
Journal	Advanced Materials
Volume	24
Issue number	46
DOIs	https://doi.org/10.1002/adma.201202685
Publication status	Published - 4 Dec 2012

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AU - Khan, Asad M.

AU - Armstrong, James P.K.

AU - Perriman, Adam W.

AU - Butts, Craig P.

AU - Eastoe, Julian

PY - 2012/12/4

Y1 - 2012/12/4

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AB - DNA chains and their movement in solvent may now be controlled simply by surfactant binding and the switching "on" and "off" of a magnetic field adding a new paradigm to the study and control, condensation and manipulation of DNA (and other biomolecules). Such control is essential for biotechnological applications such as transfection and the regulation of gene suppression, as well as in materials science concerning soft molecular self-assemblies.

KW - DNA compaction

KW - magnetic manipulation

KW - magnetic surfactants

UR - https://www.scopus.com/pages/publications/84870523896

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JO - Advanced Materials

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Magnetizing DNA and proteins using responsive surfactants

Abstract

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