Maintenance of ancestral complexity and non-metazoan genes in two basal cnidarians

Ulrich Technau; Stephen Rudd; Peter Maxwell; Paul M.K. Gordon; Michael Saina; Lauretta C. Grasso; David C. Hayward; Christoph W. Sensen; Robert Saint; Thomas W. Holstein; Eldon E. Ball; David J. Miller

doi:10.1016/j.tig.2005.09.007

Maintenance of ancestral complexity and non-metazoan genes in two basal cnidarians

Ulrich Technau^*, Stephen Rudd, Peter Maxwell, Paul M.K. Gordon, Michael Saina, Lauretta C. Grasso, David C. Hayward, Christoph W. Sensen, Robert Saint, Thomas W. Holstein, Eldon E. Ball, David J. Miller

^*Corresponding author for this work

Research output: Contribution to journal › Short survey › peer-review

266 Citations (Scopus)

Abstract

Cnidarians are among the simplest extant animals; however EST analyses reveal that they have a remarkably high level of genetic complexity. In this article, we show that the full diversity of metazoan signaling pathways is represented in this phylum, as are antagonists previously known only in chordates. Many of the cnidarian ESTs match genes previously known only in non-animal kingdoms. At least some of these represent ancient genes lost by all bilaterians examined so far, rather than genes gained by recent lateral gene transfer.

Original language	English
Pages (from-to)	633-639
Number of pages	7
Journal	Trends in Genetics
Volume	21
Issue number	12
DOIs	https://doi.org/10.1016/j.tig.2005.09.007
Publication status	Published - Dec 2005

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title = "Maintenance of ancestral complexity and non-metazoan genes in two basal cnidarians",

abstract = "Cnidarians are among the simplest extant animals; however EST analyses reveal that they have a remarkably high level of genetic complexity. In this article, we show that the full diversity of metazoan signaling pathways is represented in this phylum, as are antagonists previously known only in chordates. Many of the cnidarian ESTs match genes previously known only in non-animal kingdoms. At least some of these represent ancient genes lost by all bilaterians examined so far, rather than genes gained by recent lateral gene transfer.",

author = "Ulrich Technau and Stephen Rudd and Peter Maxwell and Gordon, {Paul M.K.} and Michael Saina and Grasso, {Lauretta C.} and Hayward, {David C.} and Sensen, {Christoph W.} and Robert Saint and Holstein, {Thomas W.} and Ball, {Eldon E.} and Miller, {David J.}",

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language = "English",

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pages = "633--639",

journal = "Trends in Genetics",

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TY - JOUR

T1 - Maintenance of ancestral complexity and non-metazoan genes in two basal cnidarians

AU - Technau, Ulrich

AU - Rudd, Stephen

AU - Maxwell, Peter

AU - Gordon, Paul M.K.

AU - Saina, Michael

AU - Grasso, Lauretta C.

AU - Hayward, David C.

AU - Sensen, Christoph W.

AU - Saint, Robert

AU - Holstein, Thomas W.

AU - Ball, Eldon E.

AU - Miller, David J.

PY - 2005/12

Y1 - 2005/12

N2 - Cnidarians are among the simplest extant animals; however EST analyses reveal that they have a remarkably high level of genetic complexity. In this article, we show that the full diversity of metazoan signaling pathways is represented in this phylum, as are antagonists previously known only in chordates. Many of the cnidarian ESTs match genes previously known only in non-animal kingdoms. At least some of these represent ancient genes lost by all bilaterians examined so far, rather than genes gained by recent lateral gene transfer.

AB - Cnidarians are among the simplest extant animals; however EST analyses reveal that they have a remarkably high level of genetic complexity. In this article, we show that the full diversity of metazoan signaling pathways is represented in this phylum, as are antagonists previously known only in chordates. Many of the cnidarian ESTs match genes previously known only in non-animal kingdoms. At least some of these represent ancient genes lost by all bilaterians examined so far, rather than genes gained by recent lateral gene transfer.

UR - http://www.scopus.com/inward/record.url?scp=27744503847&partnerID=8YFLogxK

U2 - 10.1016/j.tig.2005.09.007

DO - 10.1016/j.tig.2005.09.007

M3 - Short survey

SN - 0168-9525

VL - 21

SP - 633

EP - 639

JO - Trends in Genetics

JF - Trends in Genetics

IS - 12

ER -

Maintenance of ancestral complexity and non-metazoan genes in two basal cnidarians

Abstract

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