Maternal obesity and diabetes induces latent metabolic defects and widespread epigenetic changes in isogenic mice

Cheryl CY Li; Paul E Young; Christopher A Maloney; Sally A Eaton; Mark J. Cowley; Michael E Buckland; Thomas Preiss; Darren C Henstridge; Gregory J Cooney; Mark Febbraio; David I K Martin; Jennifer E Cropley; Catherine M Suter

doi:10.4161/epi.24656

Maternal obesity and diabetes induces latent metabolic defects and widespread epigenetic changes in isogenic mice

Cheryl CY Li, Paul E Young, Christopher A Maloney, Sally A Eaton, Mark J. Cowley, Michael E Buckland, Thomas Preiss, Darren C Henstridge, Gregory J Cooney, Mark Febbraio, David I K Martin, Jennifer E Cropley, Catherine M Suter

Research output: Contribution to journal › Article › peer-review

Abstract

Intrauterine nutrition can program metabolism, creating stable changes in physiology that may have significant health consequences. The mechanism underlying these changes is widely assumed to involve epigenetic changes to the expression of metabolic genes

Original language	English
Pages (from-to)	602-611
Journal	Epigenetics
Volume	8
Issue number	6
DOIs	https://doi.org/10.4161/epi.24656
Publication status	Published - 2013

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Li, C. CY., Young, P. E., Maloney, C. A., Eaton, S. A., Cowley, M. J., Buckland, M. E., Preiss, T., Henstridge, D. C., Cooney, G. J., Febbraio, M., Martin, D. I. K., Cropley, J. E., & Suter, C. M. (2013). Maternal obesity and diabetes induces latent metabolic defects and widespread epigenetic changes in isogenic mice. Epigenetics, 8(6), 602-611. https://doi.org/10.4161/epi.24656

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title = "Maternal obesity and diabetes induces latent metabolic defects and widespread epigenetic changes in isogenic mice",

abstract = "Intrauterine nutrition can program metabolism, creating stable changes in physiology that may have significant health consequences. The mechanism underlying these changes is widely assumed to involve epigenetic changes to the expression of metabolic genes",

author = "Li, {Cheryl CY} and Young, {Paul E} and Maloney, {Christopher A} and Eaton, {Sally A} and Cowley, {Mark J.} and Buckland, {Michael E} and Thomas Preiss and Henstridge, {Darren C} and Cooney, {Gregory J} and Mark Febbraio and Martin, {David I K} and Cropley, {Jennifer E} and Suter, {Catherine M}",

year = "2013",

doi = "10.4161/epi.24656",

language = "English",

volume = "8",

pages = "602--611",

journal = "Epigenetics",

publisher = "Landes Bioscience",

number = "6",

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AU - Li, Cheryl CY

AU - Young, Paul E

AU - Maloney, Christopher A

AU - Eaton, Sally A

AU - Cowley, Mark J.

AU - Buckland, Michael E

AU - Preiss, Thomas

AU - Henstridge, Darren C

AU - Cooney, Gregory J

AU - Febbraio, Mark

AU - Martin, David I K

AU - Cropley, Jennifer E

AU - Suter, Catherine M

PY - 2013

Y1 - 2013

N2 - Intrauterine nutrition can program metabolism, creating stable changes in physiology that may have significant health consequences. The mechanism underlying these changes is widely assumed to involve epigenetic changes to the expression of metabolic genes

AB - Intrauterine nutrition can program metabolism, creating stable changes in physiology that may have significant health consequences. The mechanism underlying these changes is widely assumed to involve epigenetic changes to the expression of metabolic genes

U2 - 10.4161/epi.24656

DO - 10.4161/epi.24656

M3 - Article

VL - 8

SP - 602

EP - 611

JO - Epigenetics

JF - Epigenetics

IS - 6

ER -

Maternal obesity and diabetes induces latent metabolic defects and widespread epigenetic changes in isogenic mice

Abstract

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