Original language | English |
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Title of host publication | Encyclopedia of Malaria |
Editors | Marcel Hommel & Peter Kremsner |
Place of Publication | Online |
Publisher | Springer New York |
Pages | 1-11pp |
Number of pages | 11 |
Volume | 1 |
Edition | Continuously updated |
ISBN (Print) | 9781461487579 |
DOIs | |
Publication status | Published - 2015 |
Abstract
The malaria parasite-infected erythrocyte is one cell inside another and, as such, is a complex multimembrane system. The host erythrocyte is bounded by a plasma membrane, and within the infected erythrocyte cytosol are parasite-derived membranous networks that manifest themselves as Maurers clefts and other tubulovesicular structures. The intraerythrocytic parasite is enclosed within a parasitophorous vacuole membrane, and the parasite itself is bounded by a plasma membrane. Within the parasite is a complex endomembrane system comprising a plethora of membrane-bound compartments (organelles). These include the parasites digestive vacuole, the apicoplast, and the mitochondrion, each of which is the site of action of at least one class of antimalarial drug.