Membrane Transport in the Malaria Parasite

Kiaran Kirk, Rowena Martin

    Research output: Chapter in Book/Report/Conference proceedingEntry for encyclopedia/dictionarypeer-review

    Abstract

    The malaria parasite-infected erythrocyte is one cell inside another and, as such, is a complex multimembrane system. The host erythrocyte is bounded by a plasma membrane, and within the infected erythrocyte cytosol are parasite-derived membranous networks that manifest themselves as Maurers clefts and other tubulovesicular structures. The intraerythrocytic parasite is enclosed within a parasitophorous vacuole membrane, and the parasite itself is bounded by a plasma membrane. Within the parasite is a complex endomembrane system comprising a plethora of membrane-bound compartments (organelles). These include the parasites digestive vacuole, the apicoplast, and the mitochondrion, each of which is the site of action of at least one class of antimalarial drug.
    Original languageEnglish
    Title of host publicationEncyclopedia of Malaria
    EditorsMarcel Hommel & Peter Kremsner
    Place of PublicationOnline
    PublisherSpringer New York
    Pages1-11pp
    Number of pages11
    Volume1
    EditionContinuously updated
    ISBN (Print)9781461487579
    DOIs
    Publication statusPublished - 2015

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