Memory B cell responses to malaria vaccines are potently inhibited by sub-protective antibody titres [Meeting Abstract]

Yeping Cai; Azza Idris; Hayley McNamara; Harry Sutton; Robert Seder; Ian Cockburn

doi:10.1002/eji.201970300

Memory B cell responses to malaria vaccines are potently inhibited by sub-protective antibody titres [Meeting Abstract]

Yeping Cai, Azza Idris, Hayley McNamara, Harry Sutton, Robert Seder, Ian Cockburn

Research output: Contribution to journal › Literature review

Abstract

The development of vaccines which induce high titres of protective antibodies has proved challenging for complex diseases such as malaria and HIV. In the case of malaria the circumsporozoite protein (CSP) antigen of Plasmodium encases the parasite and is a major vaccine candidate; however, protective antibody responses to this antigen are short-lived in vaccinated humans

Original language	English
Pages (from-to)	81-82
Journal	European Journal of Immunology
Volume	49
Issue number	S1
DOIs	https://doi.org/10.1002/eji.201970300
Publication status	Published - 2019

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title = "Memory B cell responses to malaria vaccines are potently inhibited by sub-protective antibody titres [Meeting Abstract]",

abstract = "The development of vaccines which induce high titres of protective antibodies has proved challenging for complex diseases such as malaria and HIV. In the case of malaria the circumsporozoite protein (CSP) antigen of Plasmodium encases the parasite and is a major vaccine candidate; however, protective antibody responses to this antigen are short-lived in vaccinated humans",

author = "Yeping Cai and Azza Idris and Hayley McNamara and Harry Sutton and Robert Seder and Ian Cockburn",

year = "2019",

doi = "10.1002/eji.201970300",

language = "English",

volume = "49",

pages = "81--82",

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T1 - Memory B cell responses to malaria vaccines are potently inhibited by sub-protective antibody titres [Meeting Abstract]

AU - Cai, Yeping

AU - Idris, Azza

AU - McNamara, Hayley

AU - Sutton, Harry

AU - Seder, Robert

AU - Cockburn, Ian

PY - 2019

Y1 - 2019

N2 - The development of vaccines which induce high titres of protective antibodies has proved challenging for complex diseases such as malaria and HIV. In the case of malaria the circumsporozoite protein (CSP) antigen of Plasmodium encases the parasite and is a major vaccine candidate; however, protective antibody responses to this antigen are short-lived in vaccinated humans

AB - The development of vaccines which induce high titres of protective antibodies has proved challenging for complex diseases such as malaria and HIV. In the case of malaria the circumsporozoite protein (CSP) antigen of Plasmodium encases the parasite and is a major vaccine candidate; however, protective antibody responses to this antigen are short-lived in vaccinated humans

U2 - 10.1002/eji.201970300

DO - 10.1002/eji.201970300

M3 - Literature review

VL - 49

SP - 81

EP - 82

JO - European Journal of Immunology

JF - European Journal of Immunology

IS - S1

ER -

Memory B cell responses to malaria vaccines are potently inhibited by sub-protective antibody titres [Meeting Abstract]

Abstract

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