Metallic biomaterials: Current challenges and opportunities

Karthika Prasad; Olha Bazaka; Ming Chua; Madison Rochford; Liam Fedrick; Jordan Spoor; Richard Symes; Marcus Tieppo; Cameron Collins; Alex Cao; David Markwell; Kostya Ostrikov; Kateryna Bazaka

doi:10.3390/ma10080884

Metallic biomaterials: Current challenges and opportunities

Karthika Prasad^*, Olha Bazaka, Ming Chua, Madison Rochford, Liam Fedrick, Jordan Spoor, Richard Symes, Marcus Tieppo, Cameron Collins, Alex Cao, David Markwell, Kostya Ostrikov, Kateryna Bazaka

^*Corresponding author for this work

Research output: Contribution to journal › Review article › peer-review

455 Citations (Scopus)

Abstract

Metallic biomaterials are engineered systems designed to provide internal support to biological tissues and they are being used largely in joint replacements, dental implants, orthopaedic fixations and stents. Higher biomaterial usage is associated with an increased incidence of implant-related complications due to poor implant integration, inflammation, mechanical instability, necrosis and infections, and associated prolonged patient care, pain and loss of function. In this review, we will briefly explore major representatives of metallic biomaterials along with the key existing and emerging strategies for surface and bulk modification used to improve biointegration, mechanical strength and flexibility of biometals, and discuss their compatibility with the concept of 3D printing.

Original language	English
Article number	884
Journal	Materials
Volume	10
Issue number	8
DOIs	https://doi.org/10.3390/ma10080884
Publication status	Published - 31 Jul 2017
Externally published	Yes

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abstract = "Metallic biomaterials are engineered systems designed to provide internal support to biological tissues and they are being used largely in joint replacements, dental implants, orthopaedic fixations and stents. Higher biomaterial usage is associated with an increased incidence of implant-related complications due to poor implant integration, inflammation, mechanical instability, necrosis and infections, and associated prolonged patient care, pain and loss of function. In this review, we will briefly explore major representatives of metallic biomaterials along with the key existing and emerging strategies for surface and bulk modification used to improve biointegration, mechanical strength and flexibility of biometals, and discuss their compatibility with the concept of 3D printing.",

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AU - Bazaka, Olha

AU - Chua, Ming

AU - Rochford, Madison

AU - Fedrick, Liam

AU - Spoor, Jordan

AU - Symes, Richard

AU - Tieppo, Marcus

AU - Collins, Cameron

AU - Cao, Alex

AU - Markwell, David

AU - Ostrikov, Kostya

AU - Bazaka, Kateryna

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AB - Metallic biomaterials are engineered systems designed to provide internal support to biological tissues and they are being used largely in joint replacements, dental implants, orthopaedic fixations and stents. Higher biomaterial usage is associated with an increased incidence of implant-related complications due to poor implant integration, inflammation, mechanical instability, necrosis and infections, and associated prolonged patient care, pain and loss of function. In this review, we will briefly explore major representatives of metallic biomaterials along with the key existing and emerging strategies for surface and bulk modification used to improve biointegration, mechanical strength and flexibility of biometals, and discuss their compatibility with the concept of 3D printing.

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Metallic biomaterials: Current challenges and opportunities

Abstract

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