TY - GEN
T1 - Microarray design using the Hilbert-Schmidt independence criterion
AU - Bedo, Justin
PY - 2008
Y1 - 2008
N2 - This paper explores the design problem of selecting a small subset of clones from a large pool for creation of a microarray plate. A new kernel based unsupervised feature selection method using the Hilbert-Schmidt independence criterion (hsic) is presented and evaluated on three microarray datasets: the Alon colon cancer dataset, the van 't Veer breast cancer dataset, and a multiclass cancer of unknown primary dataset. The experiments show that subsets selected by the hsic resulted in equivalent or better performance than supervised feature selection, with the added benefit that the subsets are not target specific.
AB - This paper explores the design problem of selecting a small subset of clones from a large pool for creation of a microarray plate. A new kernel based unsupervised feature selection method using the Hilbert-Schmidt independence criterion (hsic) is presented and evaluated on three microarray datasets: the Alon colon cancer dataset, the van 't Veer breast cancer dataset, and a multiclass cancer of unknown primary dataset. The experiments show that subsets selected by the hsic resulted in equivalent or better performance than supervised feature selection, with the added benefit that the subsets are not target specific.
UR - http://www.scopus.com/inward/record.url?scp=57049109258&partnerID=8YFLogxK
U2 - 10.1007/978-3-540-88436-1_25
DO - 10.1007/978-3-540-88436-1_25
M3 - Conference contribution
SN - 3540884343
SN - 9783540884347
T3 - Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
SP - 288
EP - 298
BT - 3rd IAPR International Conference on Pattern Recognition in Bioinformatics, PRIB 2008
PB - Springer Verlag
T2 - 3rd IAPR International Conference on Pattern Recognition in Bioinformatics, PRIB 2008
Y2 - 15 October 2008 through 17 October 2008
ER -