Microarray design using the Hilbert-Schmidt independence criterion

Justin Bedo*

*Corresponding author for this work

    Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

    6 Citations (Scopus)

    Abstract

    This paper explores the design problem of selecting a small subset of clones from a large pool for creation of a microarray plate. A new kernel based unsupervised feature selection method using the Hilbert-Schmidt independence criterion (hsic) is presented and evaluated on three microarray datasets: the Alon colon cancer dataset, the van 't Veer breast cancer dataset, and a multiclass cancer of unknown primary dataset. The experiments show that subsets selected by the hsic resulted in equivalent or better performance than supervised feature selection, with the added benefit that the subsets are not target specific.

    Original languageEnglish
    Title of host publication3rd IAPR International Conference on Pattern Recognition in Bioinformatics, PRIB 2008
    PublisherSpringer Verlag
    Pages288-298
    Number of pages11
    ISBN (Print)3540884343, 9783540884347
    DOIs
    Publication statusPublished - 2008
    Event3rd IAPR International Conference on Pattern Recognition in Bioinformatics, PRIB 2008 - Melbourne, VIC, Australia
    Duration: 15 Oct 200817 Oct 2008

    Publication series

    NameLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
    Volume5265 LNBI
    ISSN (Print)0302-9743
    ISSN (Electronic)1611-3349

    Conference

    Conference3rd IAPR International Conference on Pattern Recognition in Bioinformatics, PRIB 2008
    Country/TerritoryAustralia
    CityMelbourne, VIC
    Period15/10/0817/10/08

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