Mild cognitive impairment - Beyond controversies, towards a consensus: Report of the International Working Group on Mild Cognitive Impairment

B. Winblad; K. Palmer; M. Kivipelto; V. Jelic; L. Fratiglioni; L. O. Wahlund; A. Nordberg; L. Bäckman; M. Albert; O. Almkvist; H. Arai; H. Basun; K. Blennow; M. De Leon; C. Decarli; T. Erkinjuntti; E. Giacobini; C. Graff; J. Hardy; C. Jack; A. Jorm; K. Ritchie; C. Van Duijn; P. Visser; R. C. Petersen

doi:10.1111/j.1365-2796.2004.01380.x

Mild cognitive impairment - Beyond controversies, towards a consensus: Report of the International Working Group on Mild Cognitive Impairment

B. Winblad^*, K. Palmer, M. Kivipelto, V. Jelic, L. Fratiglioni, L. O. Wahlund, A. Nordberg, L. Bäckman, M. Albert, O. Almkvist, H. Arai, H. Basun, K. Blennow, M. De Leon, C. Decarli, T. Erkinjuntti, E. Giacobini, C. Graff, J. Hardy, C. JackA. Jorm, K. Ritchie, C. Van Duijn, P. Visser, R. C. Petersen

^*Corresponding author for this work

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Abstract

The First Key Symposium was held in Stockholm, Sweden, 2-5 September 2003. The aim of the symposium was to integrate clinical and epidemiological perspectives on the topic of Mild Cognitive Impairment (MCI). A multidisciplinary, international group of experts discussed the current status and future directions of MCI, with regard to clinical presentation, cognitive and functional assessment, and the role of neuroimaging, biomarkers and genetics. Agreement on new perspectives, as well as recommendations for management and future research were discussed by the international working group. The specific recommendations for the general MCI criteria include the following; (i) the person is neither normal nor demented; (ii) there is evidence of cognitive deterioration shown by either objectively measured decline over time and/or subjective report of decline by self and/or informant in conjunction with objective cognitive deficits; and (iii) activities of daily living are preserved and complex instrumental functions are either intact or minimally impaired.

Original language	English
Pages (from-to)	240-246
Number of pages	7
Journal	Journal of Internal Medicine
Volume	256
Issue number	3
DOIs	https://doi.org/10.1111/j.1365-2796.2004.01380.x
Publication status	Published - Sept 2004

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Winblad, B., Palmer, K., Kivipelto, M., Jelic, V., Fratiglioni, L., Wahlund, L. O., Nordberg, A., Bäckman, L., Albert, M., Almkvist, O., Arai, H., Basun, H., Blennow, K., De Leon, M., Decarli, C., Erkinjuntti, T., Giacobini, E., Graff, C., Hardy, J., ... Petersen, R. C. (2004). Mild cognitive impairment - Beyond controversies, towards a consensus: Report of the International Working Group on Mild Cognitive Impairment. Journal of Internal Medicine, 256(3), 240-246. https://doi.org/10.1111/j.1365-2796.2004.01380.x

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title = "Mild cognitive impairment - Beyond controversies, towards a consensus: Report of the International Working Group on Mild Cognitive Impairment",

abstract = "The First Key Symposium was held in Stockholm, Sweden, 2-5 September 2003. The aim of the symposium was to integrate clinical and epidemiological perspectives on the topic of Mild Cognitive Impairment (MCI). A multidisciplinary, international group of experts discussed the current status and future directions of MCI, with regard to clinical presentation, cognitive and functional assessment, and the role of neuroimaging, biomarkers and genetics. Agreement on new perspectives, as well as recommendations for management and future research were discussed by the international working group. The specific recommendations for the general MCI criteria include the following; (i) the person is neither normal nor demented; (ii) there is evidence of cognitive deterioration shown by either objectively measured decline over time and/or subjective report of decline by self and/or informant in conjunction with objective cognitive deficits; and (iii) activities of daily living are preserved and complex instrumental functions are either intact or minimally impaired.",

keywords = "Alzheimer's disease, Clinical criteria, Consensus, Definition, MCI, Mild cognitive impairment, Pre-clinical dementia",

author = "B. Winblad and K. Palmer and M. Kivipelto and V. Jelic and L. Fratiglioni and Wahlund, {L. O.} and A. Nordberg and L. B{\"a}ckman and M. Albert and O. Almkvist and H. Arai and H. Basun and K. Blennow and {De Leon}, M. and C. Decarli and T. Erkinjuntti and E. Giacobini and C. Graff and J. Hardy and C. Jack and A. Jorm and K. Ritchie and {Van Duijn}, C. and P. Visser and Petersen, {R. C.}",

year = "2004",

month = sep,

doi = "10.1111/j.1365-2796.2004.01380.x",

language = "English",

volume = "256",

pages = "240--246",

journal = "Journal of Internal Medicine",

issn = "0954-6820",

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Winblad, B, Palmer, K, Kivipelto, M, Jelic, V, Fratiglioni, L, Wahlund, LO, Nordberg, A, Bäckman, L, Albert, M, Almkvist, O, Arai, H, Basun, H, Blennow, K, De Leon, M, Decarli, C, Erkinjuntti, T, Giacobini, E, Graff, C, Hardy, J, Jack, C, Jorm, A, Ritchie, K, Van Duijn, C, Visser, P & Petersen, RC 2004, 'Mild cognitive impairment - Beyond controversies, towards a consensus: Report of the International Working Group on Mild Cognitive Impairment', Journal of Internal Medicine, vol. 256, no. 3, pp. 240-246. https://doi.org/10.1111/j.1365-2796.2004.01380.x

TY - JOUR

T1 - Mild cognitive impairment - Beyond controversies, towards a consensus

T2 - Report of the International Working Group on Mild Cognitive Impairment

AU - Winblad, B.

AU - Palmer, K.

AU - Kivipelto, M.

AU - Jelic, V.

AU - Fratiglioni, L.

AU - Wahlund, L. O.

AU - Nordberg, A.

AU - Bäckman, L.

AU - Albert, M.

AU - Almkvist, O.

AU - Arai, H.

AU - Basun, H.

AU - Blennow, K.

AU - De Leon, M.

AU - Decarli, C.

AU - Erkinjuntti, T.

AU - Giacobini, E.

AU - Graff, C.

AU - Hardy, J.

AU - Jack, C.

AU - Jorm, A.

AU - Ritchie, K.

AU - Van Duijn, C.

AU - Visser, P.

AU - Petersen, R. C.

PY - 2004/9

Y1 - 2004/9

N2 - The First Key Symposium was held in Stockholm, Sweden, 2-5 September 2003. The aim of the symposium was to integrate clinical and epidemiological perspectives on the topic of Mild Cognitive Impairment (MCI). A multidisciplinary, international group of experts discussed the current status and future directions of MCI, with regard to clinical presentation, cognitive and functional assessment, and the role of neuroimaging, biomarkers and genetics. Agreement on new perspectives, as well as recommendations for management and future research were discussed by the international working group. The specific recommendations for the general MCI criteria include the following; (i) the person is neither normal nor demented; (ii) there is evidence of cognitive deterioration shown by either objectively measured decline over time and/or subjective report of decline by self and/or informant in conjunction with objective cognitive deficits; and (iii) activities of daily living are preserved and complex instrumental functions are either intact or minimally impaired.

AB - The First Key Symposium was held in Stockholm, Sweden, 2-5 September 2003. The aim of the symposium was to integrate clinical and epidemiological perspectives on the topic of Mild Cognitive Impairment (MCI). A multidisciplinary, international group of experts discussed the current status and future directions of MCI, with regard to clinical presentation, cognitive and functional assessment, and the role of neuroimaging, biomarkers and genetics. Agreement on new perspectives, as well as recommendations for management and future research were discussed by the international working group. The specific recommendations for the general MCI criteria include the following; (i) the person is neither normal nor demented; (ii) there is evidence of cognitive deterioration shown by either objectively measured decline over time and/or subjective report of decline by self and/or informant in conjunction with objective cognitive deficits; and (iii) activities of daily living are preserved and complex instrumental functions are either intact or minimally impaired.

KW - Alzheimer's disease

KW - Clinical criteria

KW - Consensus

KW - Definition

KW - MCI

KW - Mild cognitive impairment

KW - Pre-clinical dementia

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U2 - 10.1111/j.1365-2796.2004.01380.x

DO - 10.1111/j.1365-2796.2004.01380.x

M3 - Article

SN - 0954-6820

VL - 256

SP - 240

EP - 246

JO - Journal of Internal Medicine

JF - Journal of Internal Medicine

IS - 3

ER -

Mild cognitive impairment - Beyond controversies, towards a consensus: Report of the International Working Group on Mild Cognitive Impairment

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