Miniaturized bio-and chemical-sensors for point-of-care monitoring of chronic kidney diseases

Antonio Tricoli; Giovanni Neri

doi:10.3390/s18040942

Miniaturized bio-and chemical-sensors for point-of-care monitoring of chronic kidney diseases

Antonio Tricoli, Giovanni Neri^*

^*Corresponding author for this work

Research output: Contribution to journal › Review article › peer-review

53 Citations (Scopus)

Abstract

This review reports the latest achievements in point-of-care (POC) sensor technologies for the monitoring of ammonia, creatinine and urea in patients suffering of chronic kidney diseases (CKDs). Abnormal levels of these nitrogen biomarkers are found in the physiological fluids, such as blood, urine and sweat, of CKD patients. Delocalized at-home monitoring of CKD biomarkers via integration of miniaturized, portable, and low cost chemical- and bio-sensors in POC devices, is an emerging approach to improve patients’ health monitoring and life quality. The successful monitoring of CKD biomarkers, performed on the different body fluids by means of sensors having strict requirements in term of size, cost, large-scale production capacity, response time and simple operation procedures for use in POC devices, is reported and discussed.

Original language	English
Article number	942
Journal	Sensors
Volume	18
Issue number	4
DOIs	https://doi.org/10.3390/s18040942
Publication status	Published - Apr 2018

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title = "Miniaturized bio-and chemical-sensors for point-of-care monitoring of chronic kidney diseases",

abstract = "This review reports the latest achievements in point-of-care (POC) sensor technologies for the monitoring of ammonia, creatinine and urea in patients suffering of chronic kidney diseases (CKDs). Abnormal levels of these nitrogen biomarkers are found in the physiological fluids, such as blood, urine and sweat, of CKD patients. Delocalized at-home monitoring of CKD biomarkers via integration of miniaturized, portable, and low cost chemical- and bio-sensors in POC devices, is an emerging approach to improve patients{\textquoteright} health monitoring and life quality. The successful monitoring of CKD biomarkers, performed on the different body fluids by means of sensors having strict requirements in term of size, cost, large-scale production capacity, response time and simple operation procedures for use in POC devices, is reported and discussed.",

keywords = "Biosensors, Chemical sensors, Kidney disease, POC testing devices",

author = "Antonio Tricoli and Giovanni Neri",

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N2 - This review reports the latest achievements in point-of-care (POC) sensor technologies for the monitoring of ammonia, creatinine and urea in patients suffering of chronic kidney diseases (CKDs). Abnormal levels of these nitrogen biomarkers are found in the physiological fluids, such as blood, urine and sweat, of CKD patients. Delocalized at-home monitoring of CKD biomarkers via integration of miniaturized, portable, and low cost chemical- and bio-sensors in POC devices, is an emerging approach to improve patients’ health monitoring and life quality. The successful monitoring of CKD biomarkers, performed on the different body fluids by means of sensors having strict requirements in term of size, cost, large-scale production capacity, response time and simple operation procedures for use in POC devices, is reported and discussed.

AB - This review reports the latest achievements in point-of-care (POC) sensor technologies for the monitoring of ammonia, creatinine and urea in patients suffering of chronic kidney diseases (CKDs). Abnormal levels of these nitrogen biomarkers are found in the physiological fluids, such as blood, urine and sweat, of CKD patients. Delocalized at-home monitoring of CKD biomarkers via integration of miniaturized, portable, and low cost chemical- and bio-sensors in POC devices, is an emerging approach to improve patients’ health monitoring and life quality. The successful monitoring of CKD biomarkers, performed on the different body fluids by means of sensors having strict requirements in term of size, cost, large-scale production capacity, response time and simple operation procedures for use in POC devices, is reported and discussed.

KW - Biosensors

KW - Chemical sensors

KW - Kidney disease

KW - POC testing devices

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VL - 18

JO - Sensors

JF - Sensors

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ER -

Miniaturized bio-and chemical-sensors for point-of-care monitoring of chronic kidney diseases

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