TY - JOUR
T1 - New tricks for old dogs
T2 - Unexpected roles for cell cycle regulators revealed using animal models
AU - Humbert, Patrick O.
AU - Brumby, Anthony M.
AU - Quinn, Leonie M.
AU - Richardson, Helena E.
PY - 2004/12
Y1 - 2004/12
N2 - Studies in animal models have revealed many surprises regarding the importance of key cell cycle regulators during animal development and homeostasis, underscoring the plasticity and redundancy of cell cycle circuitry within a whole-animal context. Moreover, checkpoint regulators, which are not essential for viability in yeast and cultured cells, play important roles in cell cycle control during development.
AB - Studies in animal models have revealed many surprises regarding the importance of key cell cycle regulators during animal development and homeostasis, underscoring the plasticity and redundancy of cell cycle circuitry within a whole-animal context. Moreover, checkpoint regulators, which are not essential for viability in yeast and cultured cells, play important roles in cell cycle control during development.
UR - http://www.scopus.com/inward/record.url?scp=7944227742&partnerID=8YFLogxK
U2 - 10.1016/j.ceb.2004.09.001
DO - 10.1016/j.ceb.2004.09.001
M3 - Review article
SN - 0955-0674
VL - 16
SP - 614
EP - 622
JO - Current Opinion in Cell Biology
JF - Current Opinion in Cell Biology
IS - 6
ER -