New tricks for old dogs: Unexpected roles for cell cycle regulators revealed using animal models

Patrick O. Humbert; Anthony M. Brumby; Leonie M. Quinn; Helena E. Richardson

doi:10.1016/j.ceb.2004.09.001

New tricks for old dogs: Unexpected roles for cell cycle regulators revealed using animal models

Patrick O. Humbert, Anthony M. Brumby, Leonie M. Quinn, Helena E. Richardson

Research output: Contribution to journal › Review article › peer-review

10 Citations (Scopus)

Abstract

Studies in animal models have revealed many surprises regarding the importance of key cell cycle regulators during animal development and homeostasis, underscoring the plasticity and redundancy of cell cycle circuitry within a whole-animal context. Moreover, checkpoint regulators, which are not essential for viability in yeast and cultured cells, play important roles in cell cycle control during development.

Original language	English
Pages (from-to)	614-622
Number of pages	9
Journal	Current Opinion in Cell Biology
Volume	16
Issue number	6
DOIs	https://doi.org/10.1016/j.ceb.2004.09.001
Publication status	Published - Dec 2004
Externally published	Yes

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10.1016/j.ceb.2004.09.001

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@article{595500aa1fd04b4e802f6c081746bec2,

title = "New tricks for old dogs: Unexpected roles for cell cycle regulators revealed using animal models",

abstract = "Studies in animal models have revealed many surprises regarding the importance of key cell cycle regulators during animal development and homeostasis, underscoring the plasticity and redundancy of cell cycle circuitry within a whole-animal context. Moreover, checkpoint regulators, which are not essential for viability in yeast and cultured cells, play important roles in cell cycle control during development.",

author = "Humbert, \{Patrick O.\} and Brumby, \{Anthony M.\} and Quinn, \{Leonie M.\} and Richardson, \{Helena E.\}",

year = "2004",

month = dec,

doi = "10.1016/j.ceb.2004.09.001",

language = "English",

volume = "16",

pages = "614--622",

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issn = "0955-0674",

publisher = "Elsevier Ltd.",

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}

TY - JOUR

T1 - New tricks for old dogs

T2 - Unexpected roles for cell cycle regulators revealed using animal models

AU - Humbert, Patrick O.

AU - Brumby, Anthony M.

AU - Quinn, Leonie M.

AU - Richardson, Helena E.

PY - 2004/12

Y1 - 2004/12

N2 - Studies in animal models have revealed many surprises regarding the importance of key cell cycle regulators during animal development and homeostasis, underscoring the plasticity and redundancy of cell cycle circuitry within a whole-animal context. Moreover, checkpoint regulators, which are not essential for viability in yeast and cultured cells, play important roles in cell cycle control during development.

AB - Studies in animal models have revealed many surprises regarding the importance of key cell cycle regulators during animal development and homeostasis, underscoring the plasticity and redundancy of cell cycle circuitry within a whole-animal context. Moreover, checkpoint regulators, which are not essential for viability in yeast and cultured cells, play important roles in cell cycle control during development.

UR - https://www.scopus.com/pages/publications/7944227742

U2 - 10.1016/j.ceb.2004.09.001

DO - 10.1016/j.ceb.2004.09.001

M3 - Review article

SN - 0955-0674

VL - 16

SP - 614

EP - 622

JO - Current Opinion in Cell Biology

JF - Current Opinion in Cell Biology

IS - 6

ER -

New tricks for old dogs: Unexpected roles for cell cycle regulators revealed using animal models

Abstract

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