On the polymorphism of benzocaine; A lowtemperature structural phase transition for form (II)

Eric J. Chan; A. David Rae; T. Richard Welberry

doi:10.1107/S0108768109018898

On the polymorphism of benzocaine; A lowtemperature structural phase transition for form (II)

Eric J. Chan, A. David Rae, T. Richard Welberry

Research output: Contribution to journal › Article › peer-review

29 Citations (Scopus)

Abstract

A low-temperature structural phase transition has been observed for form (II) of benzocaine (BZC). Lowering the temperature doubles the b-axis repeat and changes the space group from P2₁2₁2₁ to P112₁ with γ now 99.37°. The structure is twinned, the twin rule corresponding to a 21 screw rotation parallel to a. The phase transition is associated with a sequential displacement parallel to a of zigzag bi-layers of ribbons perpendicular to b*. No similar phase transition was observed for form (I) and this was attributed to the different packing symmetries of the two room-temperature polymorphic forms.

Original language	English
Pages (from-to)	509-515
Number of pages	7
Journal	Acta Crystallographica Section B: Structural Science
Volume	65
Issue number	4
DOIs	https://doi.org/10.1107/S0108768109018898
Publication status	Published - 2009

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abstract = "A low-temperature structural phase transition has been observed for form (II) of benzocaine (BZC). Lowering the temperature doubles the b-axis repeat and changes the space group from P212121 to P1121 with γ now 99.37°. The structure is twinned, the twin rule corresponding to a 21 screw rotation parallel to a. The phase transition is associated with a sequential displacement parallel to a of zigzag bi-layers of ribbons perpendicular to b*. No similar phase transition was observed for form (I) and this was attributed to the different packing symmetries of the two room-temperature polymorphic forms.",

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On the polymorphism of benzocaine; A lowtemperature structural phase transition for form (II)

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