Orientation dependence of NMR relaxation time, T(1ρ), in lipid bilayers

Frances Separovic; Bruce Cornell; Ron Pace

doi:10.1016/S0009-3084(00)00168-7

Orientation dependence of NMR relaxation time, T(1ρ), in lipid bilayers

Frances Separovic^*, Bruce Cornell, Ron Pace

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

19 Citations (Scopus)

Abstract

The orientation dependence of the low frequency NMR relaxation time, T(1ρ), of protons in aligned phospholipid bilayers was measured using ¹³C cross polarisation and direct proton experiments. The contribution of intra- and inter-molecular interactions to proton T(1ρ) was determined by using dimyristoyl phosphatidylcholine (DMPC) with one hydrocarbon chain deuterated and dispersed in perdeuterated DMPC. The results indicated that intramolecular motions on the kHz timescale were the major cause of T(1ρ) relaxation in phospholipid bilayers. (C) 2000 Elsevier Science Ireland Ltd.

Original language	English
Pages (from-to)	159-167
Number of pages	9
Journal	Chemistry and Physics of Lipids
Volume	107
Issue number	2
DOIs	https://doi.org/10.1016/S0009-3084(00)00168-7
Publication status	Published - 2000

Access to Document

10.1016/S0009-3084(00)00168-7

Cite this

@article{3195b7764e4c40d89b2e2c8d8f49acdc,

title = "Orientation dependence of NMR relaxation time, T(1ρ), in lipid bilayers",

abstract = "The orientation dependence of the low frequency NMR relaxation time, T(1ρ), of protons in aligned phospholipid bilayers was measured using 13C cross polarisation and direct proton experiments. The contribution of intra- and inter-molecular interactions to proton T(1ρ) was determined by using dimyristoyl phosphatidylcholine (DMPC) with one hydrocarbon chain deuterated and dispersed in perdeuterated DMPC. The results indicated that intramolecular motions on the kHz timescale were the major cause of T(1ρ) relaxation in phospholipid bilayers. (C) 2000 Elsevier Science Ireland Ltd.",

keywords = "Membranes, NMR, Phospholipids, Relaxation, Solid state NMR",

author = "Frances Separovic and Bruce Cornell and Ron Pace",

year = "2000",

doi = "10.1016/S0009-3084(00)00168-7",

language = "English",

volume = "107",

pages = "159--167",

journal = "Chemistry and Physics of Lipids",

issn = "0009-3084",

publisher = "Elsevier Ireland Ltd",

number = "2",

}

TY - JOUR

T1 - Orientation dependence of NMR relaxation time, T(1ρ), in lipid bilayers

AU - Separovic, Frances

AU - Cornell, Bruce

AU - Pace, Ron

PY - 2000

Y1 - 2000

N2 - The orientation dependence of the low frequency NMR relaxation time, T(1ρ), of protons in aligned phospholipid bilayers was measured using 13C cross polarisation and direct proton experiments. The contribution of intra- and inter-molecular interactions to proton T(1ρ) was determined by using dimyristoyl phosphatidylcholine (DMPC) with one hydrocarbon chain deuterated and dispersed in perdeuterated DMPC. The results indicated that intramolecular motions on the kHz timescale were the major cause of T(1ρ) relaxation in phospholipid bilayers. (C) 2000 Elsevier Science Ireland Ltd.

AB - The orientation dependence of the low frequency NMR relaxation time, T(1ρ), of protons in aligned phospholipid bilayers was measured using 13C cross polarisation and direct proton experiments. The contribution of intra- and inter-molecular interactions to proton T(1ρ) was determined by using dimyristoyl phosphatidylcholine (DMPC) with one hydrocarbon chain deuterated and dispersed in perdeuterated DMPC. The results indicated that intramolecular motions on the kHz timescale were the major cause of T(1ρ) relaxation in phospholipid bilayers. (C) 2000 Elsevier Science Ireland Ltd.

KW - Membranes

KW - NMR

KW - Phospholipids

KW - Relaxation

KW - Solid state NMR

UR - http://www.scopus.com/inward/record.url?scp=0033736861&partnerID=8YFLogxK

U2 - 10.1016/S0009-3084(00)00168-7

DO - 10.1016/S0009-3084(00)00168-7

M3 - Article

SN - 0009-3084

VL - 107

SP - 159

EP - 167

JO - Chemistry and Physics of Lipids

JF - Chemistry and Physics of Lipids

IS - 2

ER -

Orientation dependence of NMR relaxation time, T(1ρ), in lipid bilayers

Abstract

Access to Document

Other files and links

Fingerprint

Cite this