Oxazolines as directing agents in the nucleophilic addition to naphthalenes

Andrew Scott

doi:10.1071/CH03061

Oxazolines as directing agents in the nucleophilic addition to naphthalenes

Andrew Scott^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

7 Citations (Scopus)

Abstract

Oxazolines are ideal chiral auxiliaries to effect high-yielding diastereoselective transformations. These compounds activate the naphthalene π-system to nucleophilic addition. Potential applications include the total synthesis of (-)-podophyllotoxin and intramolecular cyclization of nucleophile onto an activated naphthalene.

Original language	English
Pages (from-to)	953
Number of pages	1
Journal	Australian Journal of Chemistry
Volume	56
Issue number	9
DOIs	https://doi.org/10.1071/CH03061
Publication status	Published - 2003

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abstract = "Oxazolines are ideal chiral auxiliaries to effect high-yielding diastereoselective transformations. These compounds activate the naphthalene π-system to nucleophilic addition. Potential applications include the total synthesis of (-)-podophyllotoxin and intramolecular cyclization of nucleophile onto an activated naphthalene.",

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AB - Oxazolines are ideal chiral auxiliaries to effect high-yielding diastereoselective transformations. These compounds activate the naphthalene π-system to nucleophilic addition. Potential applications include the total synthesis of (-)-podophyllotoxin and intramolecular cyclization of nucleophile onto an activated naphthalene.

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U2 - 10.1071/CH03061

DO - 10.1071/CH03061

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SP - 953

JO - Australian Journal of Chemistry

JF - Australian Journal of Chemistry

IS - 9

ER -

Oxazolines as directing agents in the nucleophilic addition to naphthalenes

Abstract

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