PathExpress: A web-based tool to identify relevant pathways in gene expression data

Nicolas Goffard; Georg Weiller

doi:10.1093/nar/gkm261

PathExpress: A web-based tool to identify relevant pathways in gene expression data

Nicolas Goffard, Georg Weiller^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

60 Citations (Scopus)

Abstract

PathExpress is a web-based tool developed to interpret gene expression data obtained from microarray experiments by identifying the most relevant metabolic pathways associated with a subset of genes (e.g. differentially expressed genes). A graphical pathway representation permits the visualization of the expressed genes in a functional context. Based on the publicly accessible KEGG Ligand database, PathExpress can be adapted to any organism and is currently available for seven Affymetrix genome arrays. About 20% of the probe sets of each array have been assigned to Enzyme Commission numbers by homology relationship and linked to corresponding metabolic pathways. PathExpress is available at http://bioinfoserver.rsb s.anu.edu.au/utils/PathExpress/.

Original language	English
Pages (from-to)	W176-W181
Journal	Nucleic Acids Research
Volume	35
Issue number	SUPPL.2
DOIs	https://doi.org/10.1093/nar/gkm261
Publication status	Published - Jul 2007

Access to Document

10.1093/nar/gkm261

Cite this

@article{b4ea983869c4434a839af621413fda78,

title = "PathExpress: A web-based tool to identify relevant pathways in gene expression data",

abstract = "PathExpress is a web-based tool developed to interpret gene expression data obtained from microarray experiments by identifying the most relevant metabolic pathways associated with a subset of genes (e.g. differentially expressed genes). A graphical pathway representation permits the visualization of the expressed genes in a functional context. Based on the publicly accessible KEGG Ligand database, PathExpress can be adapted to any organism and is currently available for seven Affymetrix genome arrays. About 20% of the probe sets of each array have been assigned to Enzyme Commission numbers by homology relationship and linked to corresponding metabolic pathways. PathExpress is available at http://bioinfoserver.rsb s.anu.edu.au/utils/PathExpress/.",

author = "Nicolas Goffard and Georg Weiller",

year = "2007",

month = jul,

doi = "10.1093/nar/gkm261",

language = "English",

volume = "35",

pages = "W176--W181",

journal = "Nucleic Acids Research",

issn = "0305-1048",

publisher = "Oxford University Press",

number = "SUPPL.2",

}

TY - JOUR

T1 - PathExpress

T2 - A web-based tool to identify relevant pathways in gene expression data

AU - Goffard, Nicolas

AU - Weiller, Georg

PY - 2007/7

Y1 - 2007/7

N2 - PathExpress is a web-based tool developed to interpret gene expression data obtained from microarray experiments by identifying the most relevant metabolic pathways associated with a subset of genes (e.g. differentially expressed genes). A graphical pathway representation permits the visualization of the expressed genes in a functional context. Based on the publicly accessible KEGG Ligand database, PathExpress can be adapted to any organism and is currently available for seven Affymetrix genome arrays. About 20% of the probe sets of each array have been assigned to Enzyme Commission numbers by homology relationship and linked to corresponding metabolic pathways. PathExpress is available at http://bioinfoserver.rsb s.anu.edu.au/utils/PathExpress/.

AB - PathExpress is a web-based tool developed to interpret gene expression data obtained from microarray experiments by identifying the most relevant metabolic pathways associated with a subset of genes (e.g. differentially expressed genes). A graphical pathway representation permits the visualization of the expressed genes in a functional context. Based on the publicly accessible KEGG Ligand database, PathExpress can be adapted to any organism and is currently available for seven Affymetrix genome arrays. About 20% of the probe sets of each array have been assigned to Enzyme Commission numbers by homology relationship and linked to corresponding metabolic pathways. PathExpress is available at http://bioinfoserver.rsb s.anu.edu.au/utils/PathExpress/.

UR - http://www.scopus.com/inward/record.url?scp=34547572234&partnerID=8YFLogxK

U2 - 10.1093/nar/gkm261

DO - 10.1093/nar/gkm261

M3 - Article

SN - 0305-1048

VL - 35

SP - W176-W181

JO - Nucleic Acids Research

JF - Nucleic Acids Research

IS - SUPPL.2

ER -

PathExpress: A web-based tool to identify relevant pathways in gene expression data

Abstract

Access to Document

Other files and links

Fingerprint

Cite this