Pd/tetraphosphine catalytic system for Cu-free Sonogashira reaction "on water"

Rong Zhou; Wei Wang; Zhi Jie Jiang; Hai Yan Fu; Xue Li Zheng; Chun Chun Zhang; Hua Chen; Rui Xiang Li

doi:10.1039/c3cy00831b

Pd/tetraphosphine catalytic system for Cu-free Sonogashira reaction "on water"

Rong Zhou, Wei Wang, Zhi Jie Jiang, Hai Yan Fu, Xue Li Zheng, Chun Chun Zhang, Hua Chen, Rui Xiang Li^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

28 Citations (Scopus)

Abstract

An efficient copper-free Sonogashira coupling reaction was performed on water at 100 °C with N,N,N′,N′-tetra(diphenylphosphinomethyl) pyridine-2,6-diamine (1) as a ligand, [Pd(η³-C₃H ₅)Cl]₂ as a catalyst precursor and K₃PO ₄ as a base. Both aryl and heteroaryl halides were successfully alkynylated in this system, and a high turnover number (TON) up to 860000 was obtained with a catalyst loading as low as 1 ppm.

Original language	English
Pages (from-to)	746-751
Number of pages	6
Journal	Catalysis Science and Technology
Volume	4
Issue number	3
DOIs	https://doi.org/10.1039/c3cy00831b
Publication status	Published - 1 Mar 2014
Externally published	Yes

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title = "Pd/tetraphosphine catalytic system for Cu-free Sonogashira reaction {"}on water{"}",

abstract = "An efficient copper-free Sonogashira coupling reaction was performed on water at 100 °C with N,N,N′,N′-tetra(diphenylphosphinomethyl) pyridine-2,6-diamine (1) as a ligand, [Pd(η3-C3H 5)Cl]2 as a catalyst precursor and K3PO 4 as a base. Both aryl and heteroaryl halides were successfully alkynylated in this system, and a high turnover number (TON) up to 860000 was obtained with a catalyst loading as low as 1 ppm.",

author = "Rong Zhou and Wei Wang and Jiang, {Zhi Jie} and Fu, {Hai Yan} and Zheng, {Xue Li} and Zhang, {Chun Chun} and Hua Chen and Li, {Rui Xiang}",

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doi = "10.1039/c3cy00831b",

language = "English",

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T1 - Pd/tetraphosphine catalytic system for Cu-free Sonogashira reaction "on water"

AU - Zhou, Rong

AU - Wang, Wei

AU - Jiang, Zhi Jie

AU - Fu, Hai Yan

AU - Zheng, Xue Li

AU - Zhang, Chun Chun

AU - Chen, Hua

AU - Li, Rui Xiang

PY - 2014/3/1

Y1 - 2014/3/1

N2 - An efficient copper-free Sonogashira coupling reaction was performed on water at 100 °C with N,N,N′,N′-tetra(diphenylphosphinomethyl) pyridine-2,6-diamine (1) as a ligand, [Pd(η3-C3H 5)Cl]2 as a catalyst precursor and K3PO 4 as a base. Both aryl and heteroaryl halides were successfully alkynylated in this system, and a high turnover number (TON) up to 860000 was obtained with a catalyst loading as low as 1 ppm.

AB - An efficient copper-free Sonogashira coupling reaction was performed on water at 100 °C with N,N,N′,N′-tetra(diphenylphosphinomethyl) pyridine-2,6-diamine (1) as a ligand, [Pd(η3-C3H 5)Cl]2 as a catalyst precursor and K3PO 4 as a base. Both aryl and heteroaryl halides were successfully alkynylated in this system, and a high turnover number (TON) up to 860000 was obtained with a catalyst loading as low as 1 ppm.

UR - http://www.scopus.com/inward/record.url?scp=84893968990&partnerID=8YFLogxK

U2 - 10.1039/c3cy00831b

DO - 10.1039/c3cy00831b

M3 - Article

SN - 2044-4753

VL - 4

SP - 746

EP - 751

JO - Catalysis Science and Technology

JF - Catalysis Science and Technology

IS - 3

ER -

Pd/tetraphosphine catalytic system for Cu-free Sonogashira reaction "on water"

Abstract

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