TY - JOUR
T1 - Peer-facilitated interventions for improving the physical health of people with schizophrenia spectrum disorders
T2 - systematic review and meta-analysis
AU - Coles, Alexandria
AU - Maksyutynska, Kateryna
AU - Knezevic, Dunja
AU - Agarwal, Sri Mahavir
AU - Strudwick, Gillian
AU - Dunbar, James A.
AU - Druss, Benjamin
AU - Selby, Peter
AU - Banfield, Michelle
AU - Hahn, Margaret K.
AU - Castle, David
N1 - Publisher Copyright:
© 2022 AMPCo Pty Ltd.
PY - 2022/10/2
Y1 - 2022/10/2
N2 - Objectives: To evaluate the efficacy of peer-facilitated interventions for improving the physical health of people with schizophrenia spectrum disorders. Study design: Systematic review and random effects meta-analysis of peer-facilitated interventions for people with serious mental illness, including schizophrenia spectrum disorders, in which physical health outcomes were assessed. Data sources: MEDLINE, PsycINFO, EMBASE, CINAHL, Web of Science, Scopus, CENTRAL, and PubMed. In addition, reference lists of reviews were examined for further relevant studies published to 10 November 2021. Data synthesis: We included fourteen publications (thirteen randomised controlled trials of ten peer-facilitated interventions, and one secondary analysis; total of 2099 participants) that assessed physical health outcomes for people with mental health conditions, including schizophrenia spectrum disorders. Intervention duration ranged from three to eighteen months; peers were involved as sole or co-leaders of the programs in group or individual sessions. Meta-analysis identified a statistically significant pooled effect on physical activity and capacity (various measures; six studies; 468 intervention, 461 control participants; standardised mean difference, +0.19 standard deviation [SD]; 95% CI, +0.06–0.32 SD; I2 = 0%); overall GRADE certainty of evidence was low. Marked study heterogeneity precluded secure conclusions regarding intervention effects on self-rated physical health, healthy eating, and body mass index. Conclusions: Peer-facilitated interventions for improving physical outcomes are feasible for people with schizophrenia spectrum disorders, a group at particular risk of certain physical health conditions. Further research is required to assess the effects of such interventions on other health-related parameters. PROSPERO registration: CRD42021283578 (retrospective).
AB - Objectives: To evaluate the efficacy of peer-facilitated interventions for improving the physical health of people with schizophrenia spectrum disorders. Study design: Systematic review and random effects meta-analysis of peer-facilitated interventions for people with serious mental illness, including schizophrenia spectrum disorders, in which physical health outcomes were assessed. Data sources: MEDLINE, PsycINFO, EMBASE, CINAHL, Web of Science, Scopus, CENTRAL, and PubMed. In addition, reference lists of reviews were examined for further relevant studies published to 10 November 2021. Data synthesis: We included fourteen publications (thirteen randomised controlled trials of ten peer-facilitated interventions, and one secondary analysis; total of 2099 participants) that assessed physical health outcomes for people with mental health conditions, including schizophrenia spectrum disorders. Intervention duration ranged from three to eighteen months; peers were involved as sole or co-leaders of the programs in group or individual sessions. Meta-analysis identified a statistically significant pooled effect on physical activity and capacity (various measures; six studies; 468 intervention, 461 control participants; standardised mean difference, +0.19 standard deviation [SD]; 95% CI, +0.06–0.32 SD; I2 = 0%); overall GRADE certainty of evidence was low. Marked study heterogeneity precluded secure conclusions regarding intervention effects on self-rated physical health, healthy eating, and body mass index. Conclusions: Peer-facilitated interventions for improving physical outcomes are feasible for people with schizophrenia spectrum disorders, a group at particular risk of certain physical health conditions. Further research is required to assess the effects of such interventions on other health-related parameters. PROSPERO registration: CRD42021283578 (retrospective).
KW - Chronic disease; Randomized controlled trial as topic
KW - Schizophrenia spectrum and other psychotic disorders
UR - http://www.scopus.com/inward/record.url?scp=85137843861&partnerID=8YFLogxK
U2 - 10.5694/mja2.51693
DO - 10.5694/mja2.51693
M3 - Review article
SN - 0025-729X
VL - 217
SP - S22-S28
JO - Medical Journal of Australia
JF - Medical Journal of Australia
IS - S7
ER -