Photoaffinity-labeled peptoids and depsipeptides by multicomponent reactions

Michael Henze, Oliver Kreye, Sebastian Brauch, Christoph Nitsche, Kai Naumann, Ludger A. Wessjohann, Bernhard Westermann*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

16 Citations (Scopus)


Photoaffinity tags can be incorporated easily into peptoids and congeners by the Ugi and Passerini multicomponent reactions. Products related to photo-methionine and photo-leucine can be accomplished by diazirine-containing building blocks. The same protocols can be used to synthesize derivatives with benzophenone photo cross-linkers.

Original languageEnglish
Article numberT04010SS
Pages (from-to)2997-3003
Number of pages7
Issue number17
Publication statusPublished - 2010
Externally publishedYes


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