Photoaffinity-labeled peptoids and depsipeptides by multicomponent reactions

Michael Henze; Oliver Kreye; Sebastian Brauch; Christoph Nitsche; Kai Naumann; Ludger A. Wessjohann; Bernhard Westermann

doi:10.1055/s-0030-1258182

Photoaffinity-labeled peptoids and depsipeptides by multicomponent reactions

Michael Henze, Oliver Kreye, Sebastian Brauch, Christoph Nitsche, Kai Naumann, Ludger A. Wessjohann, Bernhard Westermann^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

16 Citations (Scopus)

Abstract

Photoaffinity tags can be incorporated easily into peptoids and congeners by the Ugi and Passerini multicomponent reactions. Products related to photo-methionine and photo-leucine can be accomplished by diazirine-containing building blocks. The same protocols can be used to synthesize derivatives with benzophenone photo cross-linkers.

Original language	English
Article number	T04010SS
Pages (from-to)	2997-3003
Number of pages	7
Journal	Synthesis
Issue number	17
DOIs	https://doi.org/10.1055/s-0030-1258182
Publication status	Published - 2010
Externally published	Yes

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10.1055/s-0030-1258182

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title = "Photoaffinity-labeled peptoids and depsipeptides by multicomponent reactions",

abstract = "Photoaffinity tags can be incorporated easily into peptoids and congeners by the Ugi and Passerini multicomponent reactions. Products related to photo-methionine and photo-leucine can be accomplished by diazirine-containing building blocks. The same protocols can be used to synthesize derivatives with benzophenone photo cross-linkers.",

keywords = "Passerini reaction, peptoids, photo-leucine, photo-methionine, Ugi reaction",

author = "Michael Henze and Oliver Kreye and Sebastian Brauch and Christoph Nitsche and Kai Naumann and Wessjohann, {Ludger A.} and Bernhard Westermann",

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AU - Henze, Michael

AU - Kreye, Oliver

AU - Brauch, Sebastian

AU - Nitsche, Christoph

AU - Naumann, Kai

AU - Wessjohann, Ludger A.

AU - Westermann, Bernhard

PY - 2010

Y1 - 2010

N2 - Photoaffinity tags can be incorporated easily into peptoids and congeners by the Ugi and Passerini multicomponent reactions. Products related to photo-methionine and photo-leucine can be accomplished by diazirine-containing building blocks. The same protocols can be used to synthesize derivatives with benzophenone photo cross-linkers.

AB - Photoaffinity tags can be incorporated easily into peptoids and congeners by the Ugi and Passerini multicomponent reactions. Products related to photo-methionine and photo-leucine can be accomplished by diazirine-containing building blocks. The same protocols can be used to synthesize derivatives with benzophenone photo cross-linkers.

KW - Passerini reaction

KW - peptoids

KW - photo-leucine

KW - photo-methionine

KW - Ugi reaction

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DO - 10.1055/s-0030-1258182

M3 - Article

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Photoaffinity-labeled peptoids and depsipeptides by multicomponent reactions

Abstract

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