Abstract
Publisher Summary
Metabolomics is a valuable technology that provides a complete picture of the biological system. It identifies metabolite markers that underscore valuable phenotypes, assess the outcomes of engineering steps, and guide future metabolic engineering strategies. This chapter outlines the general organization of metabolite networks and illustrates broad concepts of metabolic control, regulation, and engineering. The primary aim of agricultural biotechnology is to maximize the synthesis of a product deemed desirable and to reduce the level of undesirable products. The most common metabolite detection technologies are mass spectrometry (MS) and nuclear magnetic resonance (NMR) spectroscopy. Analytical and data-mining tools are surveyed to ascertain what can be measured and how biological information can be extracted from these measurements. There has been an increase in the number, scope, and depth of applications of metabolomics in recent years. Challenges and key issues are addressed to realize the full potential of this discipline necessary for improving agriculture.
Metabolomics is a valuable technology that provides a complete picture of the biological system. It identifies metabolite markers that underscore valuable phenotypes, assess the outcomes of engineering steps, and guide future metabolic engineering strategies. This chapter outlines the general organization of metabolite networks and illustrates broad concepts of metabolic control, regulation, and engineering. The primary aim of agricultural biotechnology is to maximize the synthesis of a product deemed desirable and to reduce the level of undesirable products. The most common metabolite detection technologies are mass spectrometry (MS) and nuclear magnetic resonance (NMR) spectroscopy. Analytical and data-mining tools are surveyed to ascertain what can be measured and how biological information can be extracted from these measurements. There has been an increase in the number, scope, and depth of applications of metabolomics in recent years. Challenges and key issues are addressed to realize the full potential of this discipline necessary for improving agriculture.
| Original language | English |
|---|---|
| Title of host publication | Plant Biotechnology and Agriculture |
| Subtitle of host publication | Prospects for the 21st Century |
| Editors | Arie Altman, Paul Michael Hasegawa |
| Place of Publication | Amsterdam |
| Publisher | Academic Press |
| Chapter | 5 |
| Pages | 67-81 |
| ISBN (Print) | 9780123814661 |
| DOIs | |
| Publication status | Published - 2012 |
| Externally published | Yes |