TY - JOUR
T1 - Polyautoimmunity in Sjögren Syndrome
AU - Anaya, Juan Manuel
AU - Rojas-Villarraga, Adriana
AU - Mantilla, Ruben D.
AU - Arcos-Burgos, Mauricio
AU - Sarmiento-Monroy, Juan Camilo
N1 - Publisher Copyright:
© 2016 Elsevier Inc.
PY - 2016/8/1
Y1 - 2016/8/1
N2 - Polyautoimmunity is defined as the presence of more than one well-defined autoimmune disease (AD) in a single patient. Polyautoimmunity is a frequent condition in Sjögren syndrome (SS) and follows a grouping pattern. The most frequent ADs observed in SS are autoimmune thyroid disease, rheumatoid arthritis, and systemic lupus erythematosus. Main factors associated with polyautoimmunity in SS are tobacco smoking and some genetic variants. The study of polyautoimmunity provides important clues for elucidating the common mechanisms of autoimmne diseases (ie, the autoimmune tautology).
AB - Polyautoimmunity is defined as the presence of more than one well-defined autoimmune disease (AD) in a single patient. Polyautoimmunity is a frequent condition in Sjögren syndrome (SS) and follows a grouping pattern. The most frequent ADs observed in SS are autoimmune thyroid disease, rheumatoid arthritis, and systemic lupus erythematosus. Main factors associated with polyautoimmunity in SS are tobacco smoking and some genetic variants. The study of polyautoimmunity provides important clues for elucidating the common mechanisms of autoimmne diseases (ie, the autoimmune tautology).
KW - Autoimmune tautology
KW - Polyautoimmunity
KW - Sjögren syndrome
UR - http://www.scopus.com/inward/record.url?scp=84990973685&partnerID=8YFLogxK
U2 - 10.1016/j.rdc.2016.03.005
DO - 10.1016/j.rdc.2016.03.005
M3 - Review article
SN - 0889-857X
VL - 42
SP - 457
EP - 472
JO - Rheumatic Disease Clinics of North America
JF - Rheumatic Disease Clinics of North America
IS - 3
ER -