Polycrystalline Diamond Coating of Additively Manufactured Titanium for Biomedical Applications

Aaqil Rifai; Nhiem Tran; Desmond W. Lau; Aaron Elbourne; Hualin Zhan; Alastair D. Stacey; Edwin L.H. Mayes; Avik Sarker; Elena P. Ivanova; Russell J. Crawford; Phong A. Tran; Brant C. Gibson; Andrew D. Greentree; Elena Pirogova; Kate Fox

doi:10.1021/acsami.7b18596

Polycrystalline Diamond Coating of Additively Manufactured Titanium for Biomedical Applications

Aaqil Rifai^*, Nhiem Tran, Desmond W. Lau, Aaron Elbourne, Hualin Zhan, Alastair D. Stacey, Edwin L.H. Mayes, Avik Sarker, Elena P. Ivanova, Russell J. Crawford, Phong A. Tran, Brant C. Gibson, Andrew D. Greentree, Elena Pirogova, Kate Fox

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

62 Citations (Scopus)

Abstract

Additive manufacturing using selective laser melted titanium (SLM-Ti) is used to create bespoke items across many diverse fields such as medicine, defense, and aerospace. Despite great progress in orthopedic implant applications, such as for "just in time" implants, significant challenges remain with regards to material osseointegration and the susceptibility to bacterial colonization on the implant. Here, we show that polycrystalline diamond coatings on these titanium samples can enhance biological scaffold interaction improving medical implant applicability. The highly conformable coating exhibited excellent bonding to the substrate. Relative to uncoated SLM-Ti, the diamond coated samples showed enhanced mammalian cell growth, enriched apatite deposition, and reduced microbial S. aureus activity. These results open new opportunities for novel coatings on SLM-Ti devices in general and especially show promise for improved biomedical implants.

Original language	English
Pages (from-to)	8474-8484
Number of pages	11
Journal	ACS applied materials & interfaces
Volume	10
Issue number	10
DOIs	https://doi.org/10.1021/acsami.7b18596
Publication status	Published - 14 Mar 2018
Externally published	Yes

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Rifai, A., Tran, N., Lau, D. W., Elbourne, A., Zhan, H., Stacey, A. D., Mayes, E. L. H., Sarker, A., Ivanova, E. P., Crawford, R. J., Tran, P. A., Gibson, B. C., Greentree, A. D., Pirogova, E., & Fox, K. (2018). Polycrystalline Diamond Coating of Additively Manufactured Titanium for Biomedical Applications. ACS applied materials & interfaces, 10(10), 8474-8484. https://doi.org/10.1021/acsami.7b18596

@article{03c7320ad53f49bdb9f7ea6a7fcc2606,

title = "Polycrystalline Diamond Coating of Additively Manufactured Titanium for Biomedical Applications",

abstract = "Additive manufacturing using selective laser melted titanium (SLM-Ti) is used to create bespoke items across many diverse fields such as medicine, defense, and aerospace. Despite great progress in orthopedic implant applications, such as for {"}just in time{"} implants, significant challenges remain with regards to material osseointegration and the susceptibility to bacterial colonization on the implant. Here, we show that polycrystalline diamond coatings on these titanium samples can enhance biological scaffold interaction improving medical implant applicability. The highly conformable coating exhibited excellent bonding to the substrate. Relative to uncoated SLM-Ti, the diamond coated samples showed enhanced mammalian cell growth, enriched apatite deposition, and reduced microbial S. aureus activity. These results open new opportunities for novel coatings on SLM-Ti devices in general and especially show promise for improved biomedical implants.",

keywords = "TI6Al4V, additive manufacturing, adhesive coatings, biomaterials, diamond",

author = "Aaqil Rifai and Nhiem Tran and Lau, {Desmond W.} and Aaron Elbourne and Hualin Zhan and Stacey, {Alastair D.} and Mayes, {Edwin L.H.} and Avik Sarker and Ivanova, {Elena P.} and Crawford, {Russell J.} and Tran, {Phong A.} and Gibson, {Brant C.} and Greentree, {Andrew D.} and Elena Pirogova and Kate Fox",

note = "Publisher Copyright: {\textcopyright} 2018 American Chemical Society.",

year = "2018",

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doi = "10.1021/acsami.7b18596",

language = "English",

volume = "10",

pages = "8474--8484",

journal = "ACS applied materials & interfaces",

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Rifai, A, Tran, N, Lau, DW, Elbourne, A, Zhan, H, Stacey, AD, Mayes, ELH, Sarker, A, Ivanova, EP, Crawford, RJ, Tran, PA, Gibson, BC, Greentree, AD, Pirogova, E & Fox, K 2018, 'Polycrystalline Diamond Coating of Additively Manufactured Titanium for Biomedical Applications', ACS applied materials & interfaces, vol. 10, no. 10, pp. 8474-8484. https://doi.org/10.1021/acsami.7b18596

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T1 - Polycrystalline Diamond Coating of Additively Manufactured Titanium for Biomedical Applications

AU - Rifai, Aaqil

AU - Tran, Nhiem

AU - Lau, Desmond W.

AU - Elbourne, Aaron

AU - Zhan, Hualin

AU - Stacey, Alastair D.

AU - Mayes, Edwin L.H.

AU - Sarker, Avik

AU - Ivanova, Elena P.

AU - Crawford, Russell J.

AU - Tran, Phong A.

AU - Gibson, Brant C.

AU - Greentree, Andrew D.

AU - Pirogova, Elena

AU - Fox, Kate

PY - 2018/3/14

Y1 - 2018/3/14

N2 - Additive manufacturing using selective laser melted titanium (SLM-Ti) is used to create bespoke items across many diverse fields such as medicine, defense, and aerospace. Despite great progress in orthopedic implant applications, such as for "just in time" implants, significant challenges remain with regards to material osseointegration and the susceptibility to bacterial colonization on the implant. Here, we show that polycrystalline diamond coatings on these titanium samples can enhance biological scaffold interaction improving medical implant applicability. The highly conformable coating exhibited excellent bonding to the substrate. Relative to uncoated SLM-Ti, the diamond coated samples showed enhanced mammalian cell growth, enriched apatite deposition, and reduced microbial S. aureus activity. These results open new opportunities for novel coatings on SLM-Ti devices in general and especially show promise for improved biomedical implants.

AB - Additive manufacturing using selective laser melted titanium (SLM-Ti) is used to create bespoke items across many diverse fields such as medicine, defense, and aerospace. Despite great progress in orthopedic implant applications, such as for "just in time" implants, significant challenges remain with regards to material osseointegration and the susceptibility to bacterial colonization on the implant. Here, we show that polycrystalline diamond coatings on these titanium samples can enhance biological scaffold interaction improving medical implant applicability. The highly conformable coating exhibited excellent bonding to the substrate. Relative to uncoated SLM-Ti, the diamond coated samples showed enhanced mammalian cell growth, enriched apatite deposition, and reduced microbial S. aureus activity. These results open new opportunities for novel coatings on SLM-Ti devices in general and especially show promise for improved biomedical implants.

KW - TI6Al4V

KW - additive manufacturing

KW - adhesive coatings

KW - biomaterials

KW - diamond

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DO - 10.1021/acsami.7b18596

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JO - ACS applied materials & interfaces

JF - ACS applied materials & interfaces

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ER -

Polycrystalline Diamond Coating of Additively Manufactured Titanium for Biomedical Applications

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