TY - JOUR
T1 - Polyoxygenated Cyclohexenes and Their Chlorinated Derivatives from the Leaves of Uvaria cherrevensis
AU - Auranwiwat, Chiramet
AU - Wongsomboon, Puttandon
AU - Thaima, Thanaphat
AU - Rattanajak, Roonglawan
AU - Kamchonwongpaisan, Sumalee
AU - Willis, Anthony C.
AU - Laphookhieo, Surat
AU - Pyne, Stephen G.
AU - Limtharakul, Thunwadee
N1 - Publisher Copyright:
© 2019 American Chemical Society and American Society of Pharmacognosy.
PY - 2019/1/25
Y1 - 2019/1/25
N2 - The chemical study of leaf extracts from Uvaria cherrevensis resulted in the identification of 11 new polyoxygenated cyclohexenes, cherrevenols A-K (1-11), and a new seco-cyclohexene derivative, cherrevenol L (12). Nine known compounds (13-21) were also isolated. Three of the isolated compounds are chlorinated polyoxygenated cyclohexenes. The structures of these compounds were determined using spectroscopic methods and, in some cases (compounds 2, 6, 8, and 10), single-crystal X-ray crystallographic structural analysis or chemical correlation (compounds 6 and 7). Compounds 6 and 7 were both isolated as scalemic mixtures (ee 23-24%).
AB - The chemical study of leaf extracts from Uvaria cherrevensis resulted in the identification of 11 new polyoxygenated cyclohexenes, cherrevenols A-K (1-11), and a new seco-cyclohexene derivative, cherrevenol L (12). Nine known compounds (13-21) were also isolated. Three of the isolated compounds are chlorinated polyoxygenated cyclohexenes. The structures of these compounds were determined using spectroscopic methods and, in some cases (compounds 2, 6, 8, and 10), single-crystal X-ray crystallographic structural analysis or chemical correlation (compounds 6 and 7). Compounds 6 and 7 were both isolated as scalemic mixtures (ee 23-24%).
UR - http://www.scopus.com/inward/record.url?scp=85060556746&partnerID=8YFLogxK
U2 - 10.1021/acs.jnatprod.8b00794
DO - 10.1021/acs.jnatprod.8b00794
M3 - Article
SN - 0163-3864
VL - 82
SP - 101
EP - 110
JO - Journal of Natural Products
JF - Journal of Natural Products
IS - 1
ER -