Population genetics

Conrad J. Burden

doi:10.1016/B978-0-12-809633-8.90693-9

Population genetics

Conrad J. Burden^*

^*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

2 Citations (Scopus)

Abstract

Population genetics is concerned with genetic differences within and across populations, and the dynamics of how populations evolve as a result of the propagation of genetic mutations occurring within the germlines of individuals. This article provides a mathematical approach to the most commonly used population genetics models, including Wright-Fisher and related models, and also the less-commonly encountered Bienaymé-Galton-Watson branching model. Topics include fixation times, mutations and their relationship to substitution rates in neutral evolution, selection, multiple alleles, the diffusion limit via the forward Kolmogorov equation, multiple alleles, coalescent theory, and parameter estimation.

Original language	English
Title of host publication	Encyclopedia of Bioinformatics and Computational Biology
Subtitle of host publication	ABC of Bioinformatics
Publisher	Elsevier
Pages	759-788
Number of pages	30
Volume	1-3
ISBN (Electronic)	9780128114322
ISBN (Print)	9780128114148
DOIs	https://doi.org/10.1016/B978-0-12-809633-8.90693-9
Publication status	Published - 1 Jan 2018

Access to Document

10.1016/B978-0-12-809633-8.90693-9

Cite this

@inbook{adeb0b6393c14fb5a60e26711bd6f3d0,

title = "Population genetics",

abstract = "Population genetics is concerned with genetic differences within and across populations, and the dynamics of how populations evolve as a result of the propagation of genetic mutations occurring within the germlines of individuals. This article provides a mathematical approach to the most commonly used population genetics models, including Wright-Fisher and related models, and also the less-commonly encountered Bienaym{\'e}-Galton-Watson branching model. Topics include fixation times, mutations and their relationship to substitution rates in neutral evolution, selection, multiple alleles, the diffusion limit via the forward Kolmogorov equation, multiple alleles, coalescent theory, and parameter estimation.",

keywords = "Branching processes, Cannings exchangeable model, Coalescent, Diffusion limit, Galton-Watson, Moran model, Multiple alleles, Neutral evolution, Selection, Wright-Fisher model",

author = "Burden, {Conrad J.}",

year = "2018",

month = jan,

day = "1",

doi = "10.1016/B978-0-12-809633-8.90693-9",

language = "English",

isbn = "9780128114148",

volume = "1-3",

pages = "759--788",

booktitle = "Encyclopedia of Bioinformatics and Computational Biology",

publisher = "Elsevier",

address = "Netherlands",

}

TY - CHAP

T1 - Population genetics

AU - Burden, Conrad J.

PY - 2018/1/1

Y1 - 2018/1/1

N2 - Population genetics is concerned with genetic differences within and across populations, and the dynamics of how populations evolve as a result of the propagation of genetic mutations occurring within the germlines of individuals. This article provides a mathematical approach to the most commonly used population genetics models, including Wright-Fisher and related models, and also the less-commonly encountered Bienaymé-Galton-Watson branching model. Topics include fixation times, mutations and their relationship to substitution rates in neutral evolution, selection, multiple alleles, the diffusion limit via the forward Kolmogorov equation, multiple alleles, coalescent theory, and parameter estimation.

AB - Population genetics is concerned with genetic differences within and across populations, and the dynamics of how populations evolve as a result of the propagation of genetic mutations occurring within the germlines of individuals. This article provides a mathematical approach to the most commonly used population genetics models, including Wright-Fisher and related models, and also the less-commonly encountered Bienaymé-Galton-Watson branching model. Topics include fixation times, mutations and their relationship to substitution rates in neutral evolution, selection, multiple alleles, the diffusion limit via the forward Kolmogorov equation, multiple alleles, coalescent theory, and parameter estimation.

KW - Branching processes

KW - Cannings exchangeable model

KW - Coalescent

KW - Diffusion limit

KW - Galton-Watson

KW - Moran model

KW - Multiple alleles

KW - Neutral evolution

KW - Selection

KW - Wright-Fisher model

UR - http://www.scopus.com/inward/record.url?scp=85079739498&partnerID=8YFLogxK

U2 - 10.1016/B978-0-12-809633-8.90693-9

DO - 10.1016/B978-0-12-809633-8.90693-9

M3 - Chapter

SN - 9780128114148

VL - 1-3

SP - 759

EP - 788

BT - Encyclopedia of Bioinformatics and Computational Biology

PB - Elsevier

ER -

Population genetics

Abstract

Access to Document

Other files and links

Fingerprint

Cite this