Population study of neurodevelopmental outcomes of extremely premature infants admitted after office hours

Mohamed E. Abdel-Latif; Barbara Bajuk; Julee Oei; Kei Lui; Jennifer Bowen; Trina Vincent; Zsuzsoka Kecskés; John Edwards; Chris Wake; Anne Vimpani; Lynne Cruden; Nick Evans; Phil Beeby; David Osborn; Ingrid Rieger; Shelley Reid; Robert Guaran; Ian Callander; Jacqueline Stack; Kathryn Medlin; Sara Wilson; Lyn Downe; Basiliki Lampropoulos; Mee Fong Chin; Nadia Badawi; Alison Loughran-Fowlds; Caroline Karskens; Mary Paradisis; Martin Kluckow; Sara Sedgley; Andrew Numa; Gary Williams; Janelle Young; Mark Tracy; Melissa Luig; Jane Baird; Lee Sutton; Diane Cameron

doi:10.1111/jpc.12028

Population study of neurodevelopmental outcomes of extremely premature infants admitted after office hours

Mohamed E. Abdel-Latif^*, Barbara Bajuk, Julee Oei, Kei Lui, Jennifer Bowen, Trina Vincent, Zsuzsoka Kecskés, John Edwards, Chris Wake, Anne Vimpani, Lynne Cruden, Nick Evans, Phil Beeby, David Osborn, Ingrid Rieger, Shelley Reid, Robert Guaran, Ian Callander, Jacqueline Stack, Kathryn MedlinSara Wilson, Lyn Downe, Basiliki Lampropoulos, Mee Fong Chin, Nadia Badawi, Alison Loughran-Fowlds, Caroline Karskens, Mary Paradisis, Martin Kluckow, Sara Sedgley, Andrew Numa, Gary Williams, Janelle Young, Mark Tracy, Melissa Luig, Jane Baird, Lee Sutton, Diane Cameron

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

11 Citations (Scopus)

Abstract

Aim The aim of the study was to compare neurodevelopmental outcomes of extremely preterm infants admitted during (OH) and after (AH) office hours. Methods A retrospective review of the New South Wales and Australian Capital Territory Neonatal Intensive Care Units' (NICUs) Data Collection of all infants <29 weeks gestation admitted to New South Wales and Australian Capital Territory NICUs between January 1998 and December 2004 was conducted. The primary outcome was moderate/severe functional disability (FD) at 2-3 years follow-up defined as developmental delay (Griffiths Mental Developmental Scales general quotient or Bayley Scales of Infant Development-II mental developmental index >2 standard deviations below the mean), cerebral palsy (unable to walk without aids), deafness (requiring bilateral hearing aids) or blindness (visual acuity <6/60 in the better eye). Results Mortality and age at follow-up were comparable between the AH and OH groups. Developmental outcome was evaluated in 972 (74.9%) infants admitted during AH and 501 (74.6%) admitted during OH. FD was not significantly different between the AH and OH groups (17.1% vs. 14.8%, adjusted odds ratio 1.131, 95% confidence interval 1.131 (0.839-1.523), P = 0.420). There were no significant differences between AH and OH infants with cerebral palsy (9.6% vs. 7.6%), developmental delay (5.4% vs. 5.0%) or any other component of FD. Conclusion There is little circadian variation in mortality and adverse neurodevelopmental outcomes in an NICU network with the current model of after hours staffing and support, and sharing of NICU workload within a network.

Original language	English
Pages (from-to)	E45-E54
Journal	Journal of Paediatrics and Child Health
Volume	50
Issue number	10
DOIs	https://doi.org/10.1111/jpc.12028
Publication status	Published - 1 Oct 2014

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Abdel-Latif, M. E., Bajuk, B., Oei, J., Lui, K., Bowen, J., Vincent, T., Kecskés, Z., Edwards, J., Wake, C., Vimpani, A., Cruden, L., Evans, N., Beeby, P., Osborn, D., Rieger, I., Reid, S., Guaran, R., Callander, I., Stack, J., ... Cameron, D. (2014). Population study of neurodevelopmental outcomes of extremely premature infants admitted after office hours. Journal of Paediatrics and Child Health, 50(10), E45-E54. https://doi.org/10.1111/jpc.12028

@article{4be9683a9ed44a49aeee94db94bcf8ce,

title = "Population study of neurodevelopmental outcomes of extremely premature infants admitted after office hours",

abstract = "Aim The aim of the study was to compare neurodevelopmental outcomes of extremely preterm infants admitted during (OH) and after (AH) office hours. Methods A retrospective review of the New South Wales and Australian Capital Territory Neonatal Intensive Care Units' (NICUs) Data Collection of all infants <29 weeks gestation admitted to New South Wales and Australian Capital Territory NICUs between January 1998 and December 2004 was conducted. The primary outcome was moderate/severe functional disability (FD) at 2-3 years follow-up defined as developmental delay (Griffiths Mental Developmental Scales general quotient or Bayley Scales of Infant Development-II mental developmental index >2 standard deviations below the mean), cerebral palsy (unable to walk without aids), deafness (requiring bilateral hearing aids) or blindness (visual acuity <6/60 in the better eye). Results Mortality and age at follow-up were comparable between the AH and OH groups. Developmental outcome was evaluated in 972 (74.9%) infants admitted during AH and 501 (74.6%) admitted during OH. FD was not significantly different between the AH and OH groups (17.1% vs. 14.8%, adjusted odds ratio 1.131, 95% confidence interval 1.131 (0.839-1.523), P = 0.420). There were no significant differences between AH and OH infants with cerebral palsy (9.6% vs. 7.6%), developmental delay (5.4% vs. 5.0%) or any other component of FD. Conclusion There is little circadian variation in mortality and adverse neurodevelopmental outcomes in an NICU network with the current model of after hours staffing and support, and sharing of NICU workload within a network.",

keywords = "after office hour, neurodevelopment, office hour, premature infant",

author = "Abdel-Latif, {Mohamed E.} and Barbara Bajuk and Julee Oei and Kei Lui and Jennifer Bowen and Trina Vincent and Zsuzsoka Kecsk{\'e}s and John Edwards and Chris Wake and Anne Vimpani and Lynne Cruden and Nick Evans and Phil Beeby and David Osborn and Ingrid Rieger and Shelley Reid and Robert Guaran and Ian Callander and Jacqueline Stack and Kathryn Medlin and Sara Wilson and Lyn Downe and Basiliki Lampropoulos and Chin, {Mee Fong} and Nadia Badawi and Alison Loughran-Fowlds and Caroline Karskens and Mary Paradisis and Martin Kluckow and Sara Sedgley and Andrew Numa and Gary Williams and Janelle Young and Mark Tracy and Melissa Luig and Jane Baird and Lee Sutton and Diane Cameron",

note = "Publisher Copyright: {\textcopyright} 2012 The Authors. Journal of Paediatrics and Child Health {\textcopyright} 2012 Paediatrics and Child Health Division (Royal Australasian College of Physicians).",

year = "2014",

month = oct,

day = "1",

doi = "10.1111/jpc.12028",

language = "English",

volume = "50",

pages = "E45--E54",

journal = "Journal of Paediatrics and Child Health",

issn = "1034-4810",

publisher = "Wiley-Blackwell Publishing Ltd",

number = "10",

}

Abdel-Latif, ME, Bajuk, B, Oei, J, Lui, K, Bowen, J, Vincent, T, Kecskés, Z, Edwards, J, Wake, C, Vimpani, A, Cruden, L, Evans, N, Beeby, P, Osborn, D, Rieger, I, Reid, S, Guaran, R, Callander, I, Stack, J, Medlin, K, Wilson, S, Downe, L, Lampropoulos, B, Chin, MF, Badawi, N, Loughran-Fowlds, A, Karskens, C, Paradisis, M, Kluckow, M, Sedgley, S, Numa, A, Williams, G, Young, J, Tracy, M, Luig, M, Baird, J, Sutton, L & Cameron, D 2014, 'Population study of neurodevelopmental outcomes of extremely premature infants admitted after office hours', Journal of Paediatrics and Child Health, vol. 50, no. 10, pp. E45-E54. https://doi.org/10.1111/jpc.12028

TY - JOUR

T1 - Population study of neurodevelopmental outcomes of extremely premature infants admitted after office hours

AU - Abdel-Latif, Mohamed E.

AU - Bajuk, Barbara

AU - Oei, Julee

AU - Lui, Kei

AU - Bowen, Jennifer

AU - Vincent, Trina

AU - Kecskés, Zsuzsoka

AU - Edwards, John

AU - Wake, Chris

AU - Vimpani, Anne

AU - Cruden, Lynne

AU - Evans, Nick

AU - Beeby, Phil

AU - Osborn, David

AU - Rieger, Ingrid

AU - Reid, Shelley

AU - Guaran, Robert

AU - Callander, Ian

AU - Stack, Jacqueline

AU - Medlin, Kathryn

AU - Wilson, Sara

AU - Downe, Lyn

AU - Lampropoulos, Basiliki

AU - Chin, Mee Fong

AU - Badawi, Nadia

AU - Loughran-Fowlds, Alison

AU - Karskens, Caroline

AU - Paradisis, Mary

AU - Kluckow, Martin

AU - Sedgley, Sara

AU - Numa, Andrew

AU - Williams, Gary

AU - Young, Janelle

AU - Tracy, Mark

AU - Luig, Melissa

AU - Baird, Jane

AU - Sutton, Lee

AU - Cameron, Diane

PY - 2014/10/1

Y1 - 2014/10/1

N2 - Aim The aim of the study was to compare neurodevelopmental outcomes of extremely preterm infants admitted during (OH) and after (AH) office hours. Methods A retrospective review of the New South Wales and Australian Capital Territory Neonatal Intensive Care Units' (NICUs) Data Collection of all infants <29 weeks gestation admitted to New South Wales and Australian Capital Territory NICUs between January 1998 and December 2004 was conducted. The primary outcome was moderate/severe functional disability (FD) at 2-3 years follow-up defined as developmental delay (Griffiths Mental Developmental Scales general quotient or Bayley Scales of Infant Development-II mental developmental index >2 standard deviations below the mean), cerebral palsy (unable to walk without aids), deafness (requiring bilateral hearing aids) or blindness (visual acuity <6/60 in the better eye). Results Mortality and age at follow-up were comparable between the AH and OH groups. Developmental outcome was evaluated in 972 (74.9%) infants admitted during AH and 501 (74.6%) admitted during OH. FD was not significantly different between the AH and OH groups (17.1% vs. 14.8%, adjusted odds ratio 1.131, 95% confidence interval 1.131 (0.839-1.523), P = 0.420). There were no significant differences between AH and OH infants with cerebral palsy (9.6% vs. 7.6%), developmental delay (5.4% vs. 5.0%) or any other component of FD. Conclusion There is little circadian variation in mortality and adverse neurodevelopmental outcomes in an NICU network with the current model of after hours staffing and support, and sharing of NICU workload within a network.

AB - Aim The aim of the study was to compare neurodevelopmental outcomes of extremely preterm infants admitted during (OH) and after (AH) office hours. Methods A retrospective review of the New South Wales and Australian Capital Territory Neonatal Intensive Care Units' (NICUs) Data Collection of all infants <29 weeks gestation admitted to New South Wales and Australian Capital Territory NICUs between January 1998 and December 2004 was conducted. The primary outcome was moderate/severe functional disability (FD) at 2-3 years follow-up defined as developmental delay (Griffiths Mental Developmental Scales general quotient or Bayley Scales of Infant Development-II mental developmental index >2 standard deviations below the mean), cerebral palsy (unable to walk without aids), deafness (requiring bilateral hearing aids) or blindness (visual acuity <6/60 in the better eye). Results Mortality and age at follow-up were comparable between the AH and OH groups. Developmental outcome was evaluated in 972 (74.9%) infants admitted during AH and 501 (74.6%) admitted during OH. FD was not significantly different between the AH and OH groups (17.1% vs. 14.8%, adjusted odds ratio 1.131, 95% confidence interval 1.131 (0.839-1.523), P = 0.420). There were no significant differences between AH and OH infants with cerebral palsy (9.6% vs. 7.6%), developmental delay (5.4% vs. 5.0%) or any other component of FD. Conclusion There is little circadian variation in mortality and adverse neurodevelopmental outcomes in an NICU network with the current model of after hours staffing and support, and sharing of NICU workload within a network.

KW - after office hour

KW - neurodevelopment

KW - office hour

KW - premature infant

UR - http://www.scopus.com/inward/record.url?scp=84908244873&partnerID=8YFLogxK

U2 - 10.1111/jpc.12028

DO - 10.1111/jpc.12028

M3 - Article

SN - 1034-4810

VL - 50

SP - E45-E54

JO - Journal of Paediatrics and Child Health

JF - Journal of Paediatrics and Child Health

IS - 10

ER -

Population study of neurodevelopmental outcomes of extremely premature infants admitted after office hours

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