Potential injectable contraceptive steroids: Testosterone buciclate

Nathaniel W. Alcock; Karen J. Sanders; Alison Rodger

doi:10.1107/S1600536804000820

Potential injectable contraceptive steroids: Testosterone buciclate

Nathaniel W. Alcock^*, Karen J. Sanders, Alison Rodger

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

3 Citations (Scopus)

Abstract

The synthesis of buciclate ester of testosterone, C₃₀H ₄₆O₃, as a part of World Health Organization's programme for the development of injectable contraceptive steroids, was analyzed. The aim of the program was to develop long-acting injectable steroids for both men and women that retained an approximately constant pharmacokinetic profile. The steroid synthesis programme focused on making new esters, oximes and ethers of steroids with known contraceptive activity. The crystal structure and conformation of the steroid was the same as expected to be.

Original language	English
Pages (from-to)	o348-o349
Journal	Acta Crystallographica Section E: Structure Reports Online
Volume	60
Issue number	3
DOIs	https://doi.org/10.1107/S1600536804000820
Publication status	Published - Mar 2004
Externally published	Yes

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abstract = "The synthesis of buciclate ester of testosterone, C30H 46O3, as a part of World Health Organization's programme for the development of injectable contraceptive steroids, was analyzed. The aim of the program was to develop long-acting injectable steroids for both men and women that retained an approximately constant pharmacokinetic profile. The steroid synthesis programme focused on making new esters, oximes and ethers of steroids with known contraceptive activity. The crystal structure and conformation of the steroid was the same as expected to be.",

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year = "2004",

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AB - The synthesis of buciclate ester of testosterone, C30H 46O3, as a part of World Health Organization's programme for the development of injectable contraceptive steroids, was analyzed. The aim of the program was to develop long-acting injectable steroids for both men and women that retained an approximately constant pharmacokinetic profile. The steroid synthesis programme focused on making new esters, oximes and ethers of steroids with known contraceptive activity. The crystal structure and conformation of the steroid was the same as expected to be.

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JO - Acta Crystallographica Section E: Structure Reports Online

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Potential injectable contraceptive steroids: Testosterone buciclate

Abstract

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