TY - JOUR
T1 - Potential of metabolomics as a functional genomics tool
AU - Bino, Raoul J.
AU - Hall, Robert D.
AU - Fiehn, Oliver
AU - Kopka, Joachim
AU - Saito, Kazuki
AU - Draper, John
AU - Nikolau, Basil J.
AU - Mendes, Pedro
AU - Roessner-Tunali, Ute
AU - Beale, Michael H.
AU - Trethewey, Richard N.
AU - Lange, B. Markus
AU - Wurtele, Eve Syrkin
AU - Sumner, Lloyd W.
PY - 2004/9
Y1 - 2004/9
N2 - Metabolomics is developing as an important functional genomics tool; however, there is still room for technical improvements in both the large-scale determination of metabolites from complex plant tissues and the dissemination of metabolomics research data. For the continued maturation of metabolomics, the following three objectives need to be achieved: (i) improvement in the comprehensive coverage of the plant metabolome, (ii) facilitation of comparison of results between laboratories and experiments, and (iii) enhancement of the integration of metabolomic data with other functional genomic information. Because these challenges are widely recognized and endorsed, we propose community-based efforts to define common criteria and to initiate concerted actions directed towards the release of standard reference materials, construction of consolidated metabolite libraries, and development of metabolite-specific data-management systems.
AB - Metabolomics is developing as an important functional genomics tool; however, there is still room for technical improvements in both the large-scale determination of metabolites from complex plant tissues and the dissemination of metabolomics research data. For the continued maturation of metabolomics, the following three objectives need to be achieved: (i) improvement in the comprehensive coverage of the plant metabolome, (ii) facilitation of comparison of results between laboratories and experiments, and (iii) enhancement of the integration of metabolomic data with other functional genomic information. Because these challenges are widely recognized and endorsed, we propose community-based efforts to define common criteria and to initiate concerted actions directed towards the release of standard reference materials, construction of consolidated metabolite libraries, and development of metabolite-specific data-management systems.
UR - http://www.scopus.com/inward/record.url?scp=4444309760&partnerID=8YFLogxK
U2 - 10.1016/j.tplants.2004.07.004
DO - 10.1016/j.tplants.2004.07.004
M3 - Article
SN - 1360-1385
VL - 9
SP - 418
EP - 425
JO - Trends in Plant Science
JF - Trends in Plant Science
IS - 9
ER -