Preparative Isolation of Novel Antimicrobial Compounds from Pergidae sp. by Reversed-Phase High-Performance Liquid Chromatography

Weiping Yin; Chunjiu Zhao; Chunyan Liao; Stephen Trowell; Rodney W. Rickards

doi:10.1007/s10600-013-0501-8

Preparative Isolation of Novel Antimicrobial Compounds from Pergidae sp. by Reversed-Phase High-Performance Liquid Chromatography

Weiping Yin^*
, Chunjiu Zhao
, Chunyan Liao
, Stephen Trowell
, Rodney W. Rickards

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

7 Citations (Scopus)

Abstract

A novel macrocarpal (macrocarpal M) together with the grandinol (a known plant metabolite of Eucalptus spp.) were isolated from a methanolic extract of sawfly larvae sp. indet. (Australian sawfly, Hymenoptera:Symphyta) using the developed reversed-phase high-performance liquid chromatography (RP-HPLC) method. To the best of our knowledge, this macrocarpal M is found to have high levels of antimicrobial activity for the first time. The structures of two compounds were identified by ESI-MS, ¹H NMR, ¹³C NMR, and 2D NMR.

Original language	English
Pages (from-to)	41-45
Number of pages	5
Journal	Chemistry of Natural Compounds
Volume	49
Issue number	1
DOIs	https://doi.org/10.1007/s10600-013-0501-8
Publication status	Published - Mar 2013

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title = "Preparative Isolation of Novel Antimicrobial Compounds from Pergidae sp. by Reversed-Phase High-Performance Liquid Chromatography",

abstract = "A novel macrocarpal (macrocarpal M) together with the grandinol (a known plant metabolite of Eucalptus spp.) were isolated from a methanolic extract of sawfly larvae sp. indet. (Australian sawfly, Hymenoptera:Symphyta) using the developed reversed-phase high-performance liquid chromatography (RP-HPLC) method. To the best of our knowledge, this macrocarpal M is found to have high levels of antimicrobial activity for the first time. The structures of two compounds were identified by ESI-MS, 1H NMR, 13C NMR, and 2D NMR.",

keywords = "Pergidae sp., antimicrobial activity, formylated phloroglucinol compounds, macrocarpal M, new compound, preparative HPLC, sawfly larvae",

author = "Weiping Yin and Chunjiu Zhao and Chunyan Liao and Stephen Trowell and Rickards, \{Rodney W.\}",

year = "2013",

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T1 - Preparative Isolation of Novel Antimicrobial Compounds from Pergidae sp. by Reversed-Phase High-Performance Liquid Chromatography

AU - Yin, Weiping

AU - Zhao, Chunjiu

AU - Liao, Chunyan

AU - Trowell, Stephen

AU - Rickards, Rodney W.

PY - 2013/3

Y1 - 2013/3

N2 - A novel macrocarpal (macrocarpal M) together with the grandinol (a known plant metabolite of Eucalptus spp.) were isolated from a methanolic extract of sawfly larvae sp. indet. (Australian sawfly, Hymenoptera:Symphyta) using the developed reversed-phase high-performance liquid chromatography (RP-HPLC) method. To the best of our knowledge, this macrocarpal M is found to have high levels of antimicrobial activity for the first time. The structures of two compounds were identified by ESI-MS, 1H NMR, 13C NMR, and 2D NMR.

AB - A novel macrocarpal (macrocarpal M) together with the grandinol (a known plant metabolite of Eucalptus spp.) were isolated from a methanolic extract of sawfly larvae sp. indet. (Australian sawfly, Hymenoptera:Symphyta) using the developed reversed-phase high-performance liquid chromatography (RP-HPLC) method. To the best of our knowledge, this macrocarpal M is found to have high levels of antimicrobial activity for the first time. The structures of two compounds were identified by ESI-MS, 1H NMR, 13C NMR, and 2D NMR.

KW - Pergidae sp.

KW - antimicrobial activity

KW - formylated phloroglucinol compounds

KW - macrocarpal M

KW - new compound

KW - preparative HPLC

KW - sawfly larvae

UR - https://www.scopus.com/pages/publications/84875925686

U2 - 10.1007/s10600-013-0501-8

DO - 10.1007/s10600-013-0501-8

M3 - Article

SN - 0009-3130

VL - 49

SP - 41

EP - 45

JO - Chemistry of Natural Compounds

JF - Chemistry of Natural Compounds

IS - 1

ER -

Preparative Isolation of Novel Antimicrobial Compounds from Pergidae sp. by Reversed-Phase High-Performance Liquid Chromatography

Abstract

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