Production of terbium-152 by heavy ion reactions and proton induced spallation

B. J. Allen; G. Goozee; S. Sarkar; G. Beyer; C. Morel; A. P. Byrne

doi:10.1016/S0969-8043(00)00164-0

Production of terbium-152 by heavy ion reactions and proton induced spallation

B. J. Allen^*, G. Goozee, S. Sarkar, G. Beyer, C. Morel, A. P. Byrne

^*Corresponding author for this work

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Abstract

Terbium-152 (Tb-152) is of potential value as a radiotracer for radiolanthanides in positron emission tomography. We report the production of Tb-152 by heavy ion reactions at the ANU Tandem accelerator, and by the spallation method at the CERN proton accelerator using the on-line ISOLDE separator, obtaining microcurie and millicurie yields, respectively. After purification, a phantom image in PET is obtained which shows the feasibility of using Tb-152 for monitoring the kinetics of Tb-149 and other radiolanthanides. However, the current availability of this radioisotope will be restricted to major nuclear physics research centres. (C) 2000 Elsevier Science Ltd.

Original language	English
Pages (from-to)	53-58
Number of pages	6
Journal	Applied Radiation and Isotopes
Volume	54
Issue number	1
DOIs	https://doi.org/10.1016/S0969-8043(00)00164-0
Publication status	Published - 15 Jan 2001

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10.1016/S0969-8043(00)00164-0

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abstract = "Terbium-152 (Tb-152) is of potential value as a radiotracer for radiolanthanides in positron emission tomography. We report the production of Tb-152 by heavy ion reactions at the ANU Tandem accelerator, and by the spallation method at the CERN proton accelerator using the on-line ISOLDE separator, obtaining microcurie and millicurie yields, respectively. After purification, a phantom image in PET is obtained which shows the feasibility of using Tb-152 for monitoring the kinetics of Tb-149 and other radiolanthanides. However, the current availability of this radioisotope will be restricted to major nuclear physics research centres. (C) 2000 Elsevier Science Ltd.",

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AU - Allen, B. J.

AU - Goozee, G.

AU - Sarkar, S.

AU - Beyer, G.

AU - Morel, C.

AU - Byrne, A. P.

PY - 2001/1/15

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AB - Terbium-152 (Tb-152) is of potential value as a radiotracer for radiolanthanides in positron emission tomography. We report the production of Tb-152 by heavy ion reactions at the ANU Tandem accelerator, and by the spallation method at the CERN proton accelerator using the on-line ISOLDE separator, obtaining microcurie and millicurie yields, respectively. After purification, a phantom image in PET is obtained which shows the feasibility of using Tb-152 for monitoring the kinetics of Tb-149 and other radiolanthanides. However, the current availability of this radioisotope will be restricted to major nuclear physics research centres. (C) 2000 Elsevier Science Ltd.

KW - Heavy ions

KW - Lanthanides

KW - Positron emission tomography

KW - Production

KW - Spallation

KW - Terbium-152

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Production of terbium-152 by heavy ion reactions and proton induced spallation

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