Rat model for poly-autoimmunity

Maria Staykova*

*Corresponding author for this work

    Research output: Contribution to journalArticlepeer-review

    1 Citation (Scopus)

    Abstract

    Around 30% of the male PVG rats have very low testosterone levels. Upon immunisation with myelin basic protein in complete Freund's adjuvant they develop experimental autoimmune encephalomyelitis and adjuvant arthritis. The androgen insensitive syndrome in these rats could be used in studies on poly-autoimmunity as well as in studies on variations in the sexual differentiation of brain and behavior.

    Original languageEnglish
    Pages (from-to)84-87
    Number of pages4
    JournalAmerican Journal of Immunology
    Volume8
    Issue number3
    DOIs
    Publication statusPublished - 2012

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