Real-time DNA detection using Pt nanoparticle-decorated reduced graphene oxide field-effect transistors

Zongyou Yin; Qiyuan He; Xiao Huang; Juan Zhang; Shixin Wu; Peng Chen; Gang Lu; Qichun Zhang; Qingyu Yan; Hua Zhang

doi:10.1039/c1nr11149c

Real-time DNA detection using Pt nanoparticle-decorated reduced graphene oxide field-effect transistors

Zongyou Yin, Qiyuan He, Xiao Huang, Juan Zhang, Shixin Wu, Peng Chen, Gang Lu, Qichun Zhang, Qingyu Yan, Hua Zhang^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

188 Citations (Scopus)

Abstract

A large-area, continuous, few-layer reduced graphene oxide (rGO) thin film has been fabricated on a Si/SiO ₂ wafer using the Langmuir-Blodgett (LB) method followed by thermal reduction. After photochemical reduction of Pt nanoparticles (PtNPs) on rGO, the obtained PtNPs/rGO composite is employed as the conductive channel in a solution-gated field effect transistor (FET), which is then used for real-time detection of hybridization of single-stranded DNA (ssDNA) with high sensitivity (2.4 nM). Such a simple, but effective method for fabrication of rGO-based transistors shows great potential for mass-production of graphene-based electronic biosensors.

Original language	English
Pages (from-to)	293-297
Number of pages	5
Journal	Nanoscale
Volume	4
Issue number	1
DOIs	https://doi.org/10.1039/c1nr11149c
Publication status	Published - 7 Jan 2012
Externally published	Yes

Access to Document

10.1039/c1nr11149c

Cite this

@article{b5d013844a8d427183536b086e9b51d0,

title = "Real-time DNA detection using Pt nanoparticle-decorated reduced graphene oxide field-effect transistors",

abstract = "A large-area, continuous, few-layer reduced graphene oxide (rGO) thin film has been fabricated on a Si/SiO 2 wafer using the Langmuir-Blodgett (LB) method followed by thermal reduction. After photochemical reduction of Pt nanoparticles (PtNPs) on rGO, the obtained PtNPs/rGO composite is employed as the conductive channel in a solution-gated field effect transistor (FET), which is then used for real-time detection of hybridization of single-stranded DNA (ssDNA) with high sensitivity (2.4 nM). Such a simple, but effective method for fabrication of rGO-based transistors shows great potential for mass-production of graphene-based electronic biosensors.",

author = "Zongyou Yin and Qiyuan He and Xiao Huang and Juan Zhang and Shixin Wu and Peng Chen and Gang Lu and Qichun Zhang and Qingyu Yan and Hua Zhang",

year = "2012",

month = jan,

day = "7",

doi = "10.1039/c1nr11149c",

language = "English",

volume = "4",

pages = "293--297",

journal = "Nanoscale",

issn = "2040-3364",

publisher = "Royal Society of Chemistry",

number = "1",

}

TY - JOUR

T1 - Real-time DNA detection using Pt nanoparticle-decorated reduced graphene oxide field-effect transistors

AU - Yin, Zongyou

AU - He, Qiyuan

AU - Huang, Xiao

AU - Zhang, Juan

AU - Wu, Shixin

AU - Chen, Peng

AU - Lu, Gang

AU - Zhang, Qichun

AU - Yan, Qingyu

AU - Zhang, Hua

PY - 2012/1/7

Y1 - 2012/1/7

N2 - A large-area, continuous, few-layer reduced graphene oxide (rGO) thin film has been fabricated on a Si/SiO 2 wafer using the Langmuir-Blodgett (LB) method followed by thermal reduction. After photochemical reduction of Pt nanoparticles (PtNPs) on rGO, the obtained PtNPs/rGO composite is employed as the conductive channel in a solution-gated field effect transistor (FET), which is then used for real-time detection of hybridization of single-stranded DNA (ssDNA) with high sensitivity (2.4 nM). Such a simple, but effective method for fabrication of rGO-based transistors shows great potential for mass-production of graphene-based electronic biosensors.

AB - A large-area, continuous, few-layer reduced graphene oxide (rGO) thin film has been fabricated on a Si/SiO 2 wafer using the Langmuir-Blodgett (LB) method followed by thermal reduction. After photochemical reduction of Pt nanoparticles (PtNPs) on rGO, the obtained PtNPs/rGO composite is employed as the conductive channel in a solution-gated field effect transistor (FET), which is then used for real-time detection of hybridization of single-stranded DNA (ssDNA) with high sensitivity (2.4 nM). Such a simple, but effective method for fabrication of rGO-based transistors shows great potential for mass-production of graphene-based electronic biosensors.

UR - https://www.scopus.com/pages/publications/83455225430

U2 - 10.1039/c1nr11149c

DO - 10.1039/c1nr11149c

M3 - Article

SN - 2040-3364

VL - 4

SP - 293

EP - 297

JO - Nanoscale

JF - Nanoscale

IS - 1

ER -

Real-time DNA detection using Pt nanoparticle-decorated reduced graphene oxide field-effect transistors

Abstract

Access to Document

Other files and links

Fingerprint

Cite this