Recent advances in ion channel research

Shin Ho Chung*, Serdar Kuyucak

*Corresponding author for this work

    Research output: Contribution to journalReview articlepeer-review

    89 Citations (Scopus)

    Abstract

    The field of ion channels has entered into a rapid phase of development in the last few years, partly due to the breakthroughs in determination of the crystal structures of membrane proteins and advances in computer simulations of biomolecules. These advances have finally enabled the long-dreamed goal of relating function of a channel to its underlying molecular structure. Here we present simplified accounts of the competing permeation theories and then discuss their application to the potassium, gramicidin A and calcium channels.

    Original languageEnglish
    Pages (from-to)267-286
    Number of pages20
    JournalBiochimica et Biophysica Acta - Biomembranes
    Volume1565
    Issue number2
    DOIs
    Publication statusPublished - 11 Oct 2002

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