TY - GEN
T1 - Representing association classification rules mined from health data
AU - Chen, Jie
AU - He, Hongxing
AU - Li, Jiuyong
AU - Jin, Huidong
AU - McAullay, Damien
AU - Williams, Graham
AU - Sparks, Ross
AU - Kelman, Chris
PY - 2005
Y1 - 2005
N2 - An association classification algorithm has been developed to explore adverse drug reactions in a large medical transaction dataset with unbalanced classes. Rules discovered can be used to alert medical practitioners when prescribing drugs, to certain categories of patients, to potential adverse effects. We assess the rules using survival charts and propose two kinds of probability trees to present them. Both of them represent the risk of given adverse drug reaction for certain categories of patients in terms of risk ratios, which are familiar to medical practitioners. The first approach shows risk ratios when all rule conditions apply. The second presents the risk associated with a single risk factor with other parts of the rule identifying the cohort of the patient subpopulation. Thus, the probability trees can present clearly the risk of specific adverse drug reactions to prescribers.
AB - An association classification algorithm has been developed to explore adverse drug reactions in a large medical transaction dataset with unbalanced classes. Rules discovered can be used to alert medical practitioners when prescribing drugs, to certain categories of patients, to potential adverse effects. We assess the rules using survival charts and propose two kinds of probability trees to present them. Both of them represent the risk of given adverse drug reaction for certain categories of patients in terms of risk ratios, which are familiar to medical practitioners. The first approach shows risk ratios when all rule conditions apply. The second presents the risk associated with a single risk factor with other parts of the rule identifying the cohort of the patient subpopulation. Thus, the probability trees can present clearly the risk of specific adverse drug reactions to prescribers.
UR - http://www.scopus.com/inward/record.url?scp=33745292794&partnerID=8YFLogxK
U2 - 10.1007/11553939_170
DO - 10.1007/11553939_170
M3 - Conference contribution
SN - 3540288961
SN - 9783540288961
T3 - Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
SP - 1225
EP - 1231
BT - Knowledge-Based Intelligent Information and Engineering Systems - 9th International Conference, KES 2005, Proceedings
PB - Springer Verlag
T2 - 9th International Conference on Knowledge-Based Intelligent Information and Engineering Systems, KES 2005
Y2 - 14 September 2005 through 16 September 2005
ER -