Selective binding and release of aspirin by an encapsulating receptor

Thanh V. Nguyen; Hiroshi Yoshida; Michael S. Sherburn

doi:10.1039/c0cc00422g

Selective binding and release of aspirin by an encapsulating receptor

Thanh V. Nguyen, Hiroshi Yoshida, Michael S. Sherburn

Research output: Contribution to journal › Article › peer-review

10 Citations (Scopus)

Abstract

The selective binding of aspirin deep inside superbowl synthetic hosts is reported. Evidence for a two-point binding mode of the drug by the host is presented. Both the strength of aspirin binding and the rate of its release are manipulated by altering the substituents about the host's aperture.

Original language	English
Pages (from-to)	5921-5923
Number of pages	3
Journal	Chemical Communications
Volume	46
Issue number	32
DOIs	https://doi.org/10.1039/c0cc00422g
Publication status	Published - 28 Aug 2010

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title = "Selective binding and release of aspirin by an encapsulating receptor",

abstract = "The selective binding of aspirin deep inside superbowl synthetic hosts is reported. Evidence for a two-point binding mode of the drug by the host is presented. Both the strength of aspirin binding and the rate of its release are manipulated by altering the substituents about the host's aperture.",

author = "Nguyen, {Thanh V.} and Hiroshi Yoshida and Sherburn, {Michael S.}",

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AU - Nguyen, Thanh V.

AU - Yoshida, Hiroshi

AU - Sherburn, Michael S.

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N2 - The selective binding of aspirin deep inside superbowl synthetic hosts is reported. Evidence for a two-point binding mode of the drug by the host is presented. Both the strength of aspirin binding and the rate of its release are manipulated by altering the substituents about the host's aperture.

AB - The selective binding of aspirin deep inside superbowl synthetic hosts is reported. Evidence for a two-point binding mode of the drug by the host is presented. Both the strength of aspirin binding and the rate of its release are manipulated by altering the substituents about the host's aperture.

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U2 - 10.1039/c0cc00422g

DO - 10.1039/c0cc00422g

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JO - Chemical Communications

JF - Chemical Communications

IS - 32

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Selective binding and release of aspirin by an encapsulating receptor

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