Stationary distribution of a 2-island 2-allele Wright–Fisher diffusion model with slow mutation and migration rates

Conrad J. Burden*, Robert C. Griffiths

*Corresponding author for this work

    Research output: Contribution to journalArticlepeer-review

    4 Citations (Scopus)

    Abstract

    The stationary distribution of the diffusion limit of the 2-island, 2-allele Wright–Fisher with small but otherwise arbitrary mutation and migration rates is investigated. Following a method developed by Burden and Tang (2016, 2017) for approximating the forward Kolmogorov equation, the stationary distribution is obtained to leading order as a set of line densities on the edges of the sample space, corresponding to states for which one island is bi-allelic and the other island is non-segregating, and a set of point masses at the corners of the sample space, corresponding to states for which both islands are simultaneously non-segregating. Analytic results for the corner probabilities and line densities are verified independently using the backward generator and for the corner probabilities using the coalescent.

    Original languageEnglish
    Pages (from-to)70-80
    Number of pages11
    JournalTheoretical Population Biology
    Volume124
    DOIs
    Publication statusPublished - Dec 2018

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