TY - JOUR
T1 - Stationary distribution of a 2-island 2-allele Wright–Fisher diffusion model with slow mutation and migration rates
AU - Burden, Conrad J.
AU - Griffiths, Robert C.
N1 - Publisher Copyright:
© 2018 Elsevier Inc.
PY - 2018/12
Y1 - 2018/12
N2 - The stationary distribution of the diffusion limit of the 2-island, 2-allele Wright–Fisher with small but otherwise arbitrary mutation and migration rates is investigated. Following a method developed by Burden and Tang (2016, 2017) for approximating the forward Kolmogorov equation, the stationary distribution is obtained to leading order as a set of line densities on the edges of the sample space, corresponding to states for which one island is bi-allelic and the other island is non-segregating, and a set of point masses at the corners of the sample space, corresponding to states for which both islands are simultaneously non-segregating. Analytic results for the corner probabilities and line densities are verified independently using the backward generator and for the corner probabilities using the coalescent.
AB - The stationary distribution of the diffusion limit of the 2-island, 2-allele Wright–Fisher with small but otherwise arbitrary mutation and migration rates is investigated. Following a method developed by Burden and Tang (2016, 2017) for approximating the forward Kolmogorov equation, the stationary distribution is obtained to leading order as a set of line densities on the edges of the sample space, corresponding to states for which one island is bi-allelic and the other island is non-segregating, and a set of point masses at the corners of the sample space, corresponding to states for which both islands are simultaneously non-segregating. Analytic results for the corner probabilities and line densities are verified independently using the backward generator and for the corner probabilities using the coalescent.
KW - Diffusion process
KW - Migration
KW - Subdivided population
UR - http://www.scopus.com/inward/record.url?scp=85055033068&partnerID=8YFLogxK
U2 - 10.1016/j.tpb.2018.09.004
DO - 10.1016/j.tpb.2018.09.004
M3 - Article
SN - 0040-5809
VL - 124
SP - 70
EP - 80
JO - Theoretical Population Biology
JF - Theoretical Population Biology
ER -