Stictic acid derivatives from the lichen Usnea articulata and their antioxidant activities

Françoise Lohezic-Le Devehat; Sophie Tomasi; John A. Elix; Aurélie Bernard; Isabelle Rouaud; Philippe Uriac; Joël Boustie

doi:10.1021/np070145k

Stictic acid derivatives from the lichen Usnea articulata and their antioxidant activities

Françoise Lohezic-Le Devehat^*, Sophie Tomasi, John A. Elix, Aurélie Bernard, Isabelle Rouaud, Philippe Uriac, Joël Boustie

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

94 Citations (Scopus)

Abstract

Two new β-orcinol depsidones, 1 and 2, together with 13 known compounds were isolated from the lichen Usnea articulata. The structures of 1 and 2 were elucidated by spectroscopic analyses and those of known compounds by comparison of their spectroscopic data with literature values or by direct comparison with authentic standards. Compounds 1, 2, and 5 exhibited moderate antiradical activity in the 1,1-diphenyl-2-picrylhydrazyl (DPPH) assay. The depsidones 4 and 5 showed better superoxide anion scavenging activity (IC ₅₀ = 566 and 580 μM, respectively) than quercetin (IC₅₀ = 754 μM).

Original language	English
Pages (from-to)	1218-1220
Number of pages	3
Journal	Journal of Natural Products
Volume	70
Issue number	7
DOIs	https://doi.org/10.1021/np070145k
Publication status	Published - Jul 2007

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title = "Stictic acid derivatives from the lichen Usnea articulata and their antioxidant activities",

abstract = "Two new β-orcinol depsidones, 1 and 2, together with 13 known compounds were isolated from the lichen Usnea articulata. The structures of 1 and 2 were elucidated by spectroscopic analyses and those of known compounds by comparison of their spectroscopic data with literature values or by direct comparison with authentic standards. Compounds 1, 2, and 5 exhibited moderate antiradical activity in the 1,1-diphenyl-2-picrylhydrazyl (DPPH) assay. The depsidones 4 and 5 showed better superoxide anion scavenging activity (IC 50 = 566 and 580 μM, respectively) than quercetin (IC50 = 754 μM).",

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T1 - Stictic acid derivatives from the lichen Usnea articulata and their antioxidant activities

AU - Lohezic-Le Devehat, Françoise

AU - Tomasi, Sophie

AU - Elix, John A.

AU - Bernard, Aurélie

AU - Rouaud, Isabelle

AU - Uriac, Philippe

AU - Boustie, Joël

PY - 2007/7

Y1 - 2007/7

N2 - Two new β-orcinol depsidones, 1 and 2, together with 13 known compounds were isolated from the lichen Usnea articulata. The structures of 1 and 2 were elucidated by spectroscopic analyses and those of known compounds by comparison of their spectroscopic data with literature values or by direct comparison with authentic standards. Compounds 1, 2, and 5 exhibited moderate antiradical activity in the 1,1-diphenyl-2-picrylhydrazyl (DPPH) assay. The depsidones 4 and 5 showed better superoxide anion scavenging activity (IC 50 = 566 and 580 μM, respectively) than quercetin (IC50 = 754 μM).

AB - Two new β-orcinol depsidones, 1 and 2, together with 13 known compounds were isolated from the lichen Usnea articulata. The structures of 1 and 2 were elucidated by spectroscopic analyses and those of known compounds by comparison of their spectroscopic data with literature values or by direct comparison with authentic standards. Compounds 1, 2, and 5 exhibited moderate antiradical activity in the 1,1-diphenyl-2-picrylhydrazyl (DPPH) assay. The depsidones 4 and 5 showed better superoxide anion scavenging activity (IC 50 = 566 and 580 μM, respectively) than quercetin (IC50 = 754 μM).

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DO - 10.1021/np070145k

M3 - Article

SN - 0163-3864

VL - 70

SP - 1218

EP - 1220

JO - Journal of Natural Products

JF - Journal of Natural Products

IS - 7

ER -

Stictic acid derivatives from the lichen Usnea articulata and their antioxidant activities

Abstract

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