Abstract
The gasdermin family of cell death executor proteins are activated by different proteases under different physiological conditions. A recent study by Deng et al. in Nature revealed that the cysteine protease SpeB from the human pathogen Streptococcus pyogenes directly cleaves and activates Gasdermin A to induce pyroptosis in skin cells.
Original language | English |
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Pages (from-to) | 410-412 |
Number of pages | 3 |
Journal | Cell Host and Microbe |
Volume | 30 |
Issue number | 4 |
DOIs |
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Publication status | Published - 13 Apr 2022 |