Structure-activity delineation of quinones related to the biologically active Calothrixin B

Paul H. Bernardo; Christina L.L. Chai; Maurice Le Guen; Geoffrey D. Smith; Paul Waring

doi:10.1016/j.bmcl.2006.09.090

Structure-activity delineation of quinones related to the biologically active Calothrixin B

Paul H. Bernardo, Christina L.L. Chai^*, Maurice Le Guen, Geoffrey D. Smith, Paul Waring

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

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Abstract

Quinones such as Calothrixins A and B display a range of biological properties. As part of our ongoing studies to elucidate the mechanism of action of the Calothrixins, several related quinones were synthesized and tested for biological activity. The results of the structure-activity relationship (SAR) studies are reported here.

Original language	English
Pages (from-to)	82-85
Number of pages	4
Journal	Bioorganic and Medicinal Chemistry Letters
Volume	17
Issue number	1
DOIs	https://doi.org/10.1016/j.bmcl.2006.09.090
Publication status	Published - 1 Jan 2007

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title = "Structure-activity delineation of quinones related to the biologically active Calothrixin B",

abstract = "Quinones such as Calothrixins A and B display a range of biological properties. As part of our ongoing studies to elucidate the mechanism of action of the Calothrixins, several related quinones were synthesized and tested for biological activity. The results of the structure-activity relationship (SAR) studies are reported here.",

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AU - Guen, Maurice Le

AU - Smith, Geoffrey D.

AU - Waring, Paul

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AB - Quinones such as Calothrixins A and B display a range of biological properties. As part of our ongoing studies to elucidate the mechanism of action of the Calothrixins, several related quinones were synthesized and tested for biological activity. The results of the structure-activity relationship (SAR) studies are reported here.

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JO - Bioorganic and Medicinal Chemistry Letters

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Structure-activity delineation of quinones related to the biologically active Calothrixin B

Abstract

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