Studies in macrolide synthesis: A sequential aldol/glycosylation approach to the synthesis of concanamycin A

Ian Paterson; Malcolm D. McLeod

doi:10.1016/0040-4039(95)01913-3

Studies in macrolide synthesis: A sequential aldol/glycosylation approach to the synthesis of concanamycin A

Ian Paterson^*, Malcolm D. McLeod

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

32 Citations (Scopus)

Abstract

The C₁₉-C₂₈ model fragment 2 of concanamycin A (1) was prepared by a Mukaiyama aldol reaction between silyl enol ether 11 and aldehyde 4 to give 7, followed by glycosylation with activated sugar 14 or 15.

Original language	English
Pages (from-to)	9065-9068
Number of pages	4
Journal	Tetrahedron Letters
Volume	36
Issue number	49
DOIs	https://doi.org/10.1016/0040-4039(95)01913-3
Publication status	Published - 4 Dec 1995
Externally published	Yes

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title = "Studies in macrolide synthesis: A sequential aldol/glycosylation approach to the synthesis of concanamycin A",

abstract = "The C19-C28 model fragment 2 of concanamycin A (1) was prepared by a Mukaiyama aldol reaction between silyl enol ether 11 and aldehyde 4 to give 7, followed by glycosylation with activated sugar 14 or 15.",

author = "Ian Paterson and McLeod, {Malcolm D.}",

year = "1995",

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doi = "10.1016/0040-4039(95)01913-3",

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T1 - Studies in macrolide synthesis

T2 - A sequential aldol/glycosylation approach to the synthesis of concanamycin A

AU - Paterson, Ian

AU - McLeod, Malcolm D.

PY - 1995/12/4

Y1 - 1995/12/4

N2 - The C19-C28 model fragment 2 of concanamycin A (1) was prepared by a Mukaiyama aldol reaction between silyl enol ether 11 and aldehyde 4 to give 7, followed by glycosylation with activated sugar 14 or 15.

AB - The C19-C28 model fragment 2 of concanamycin A (1) was prepared by a Mukaiyama aldol reaction between silyl enol ether 11 and aldehyde 4 to give 7, followed by glycosylation with activated sugar 14 or 15.

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U2 - 10.1016/0040-4039(95)01913-3

DO - 10.1016/0040-4039(95)01913-3

M3 - Article

AN - SCOPUS:0028858247

SN - 0040-4039

VL - 36

SP - 9065

EP - 9068

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 49

ER -

Studies in macrolide synthesis: A sequential aldol/glycosylation approach to the synthesis of concanamycin A

Abstract

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