Studies in macrolide synthesis: Stereocontrolled synthesis of a C1-C13 segment of concanamycin A

Ian Paterson*, Malcolm D. McLeod

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

29 Citations (Scopus)

Abstract

The C1-C13 segment 6 of concanamycin A (1) was prepared by a highly stereocontrolled route (87% overall ds) in 16 steps from the ester 9. Key steps are the one-pot aldol/reduction, 8 → 12, and the HWE reaction, 18 + 19 → 6.

Original languageEnglish
Pages (from-to)4183-4186
Number of pages4
JournalTetrahedron Letters
Volume38
Issue number23
DOIs
Publication statusPublished - 9 Jun 1997

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