Susceptibility profiles, molecular epidemiology, and detection of KPC-producing Escherichia coli isolates from the New York City vicinity

David Landman, Carl Urban, Martin Bäcker, Paul Kelly, Neha Shah, Elizabeth Babu, Simona Bratu, John Quale*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

25 Citations (Scopus)

Abstract

The detection of Enterobacteriaceae carrying the carbapenemase KPC has been problematic. Thirty isolates of KPC-possessing Escherichia coli were gathered from hospitals in New York City and Connecticut. The imipenem, meropenem, doripenem, and ertapenem MIC50 values were 4, 2, 1, and 4 μg/ml, respectively. Over half of the isolates belonged to a single ribotype. Using an ertapenem breakpoint of 0.25 μg/ml would efficiently detect these isolates.

Original languageEnglish
Pages (from-to)4604-4607
Number of pages4
JournalJournal of Clinical Microbiology
Volume48
Issue number12
DOIs
Publication statusPublished - Dec 2010
Externally publishedYes

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