Susceptibility profiles, molecular epidemiology, and detection of KPC-producing Escherichia coli isolates from the New York City vicinity

David Landman; Carl Urban; Martin Bäcker; Paul Kelly; Neha Shah; Elizabeth Babu; Simona Bratu; John Quale

doi:10.1128/JCM.01143-10

Susceptibility profiles, molecular epidemiology, and detection of KPC-producing Escherichia coli isolates from the New York City vicinity

David Landman, Carl Urban, Martin Bäcker, Paul Kelly, Neha Shah, Elizabeth Babu, Simona Bratu, John Quale^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

25 Citations (Scopus)

Abstract

The detection of Enterobacteriaceae carrying the carbapenemase KPC has been problematic. Thirty isolates of KPC-possessing Escherichia coli were gathered from hospitals in New York City and Connecticut. The imipenem, meropenem, doripenem, and ertapenem MIC₅₀ values were 4, 2, 1, and 4 μg/ml, respectively. Over half of the isolates belonged to a single ribotype. Using an ertapenem breakpoint of 0.25 μg/ml would efficiently detect these isolates.

Original language	English
Pages (from-to)	4604-4607
Number of pages	4
Journal	Journal of Clinical Microbiology
Volume	48
Issue number	12
DOIs	https://doi.org/10.1128/JCM.01143-10
Publication status	Published - Dec 2010
Externally published	Yes

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title = "Susceptibility profiles, molecular epidemiology, and detection of KPC-producing Escherichia coli isolates from the New York City vicinity",

abstract = "The detection of Enterobacteriaceae carrying the carbapenemase KPC has been problematic. Thirty isolates of KPC-possessing Escherichia coli were gathered from hospitals in New York City and Connecticut. The imipenem, meropenem, doripenem, and ertapenem MIC50 values were 4, 2, 1, and 4 μg/ml, respectively. Over half of the isolates belonged to a single ribotype. Using an ertapenem breakpoint of 0.25 μg/ml would efficiently detect these isolates.",

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AU - Landman, David

AU - Urban, Carl

AU - Bäcker, Martin

AU - Kelly, Paul

AU - Shah, Neha

AU - Babu, Elizabeth

AU - Bratu, Simona

AU - Quale, John

PY - 2010/12

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AB - The detection of Enterobacteriaceae carrying the carbapenemase KPC has been problematic. Thirty isolates of KPC-possessing Escherichia coli were gathered from hospitals in New York City and Connecticut. The imipenem, meropenem, doripenem, and ertapenem MIC50 values were 4, 2, 1, and 4 μg/ml, respectively. Over half of the isolates belonged to a single ribotype. Using an ertapenem breakpoint of 0.25 μg/ml would efficiently detect these isolates.

UR - https://www.scopus.com/pages/publications/78650056189

U2 - 10.1128/JCM.01143-10

DO - 10.1128/JCM.01143-10

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ER -

Susceptibility profiles, molecular epidemiology, and detection of KPC-producing Escherichia coli isolates from the New York City vicinity

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