Synthesis of MUC1-lipopeptide chimeras

Brendan L. Wilkinson, Lara R. Malins, Candy K.Y. Chun, Richard J. Payne

Research output: Contribution to journalArticlepeer-review

39 Citations (Scopus)


An efficient method for the convergent assembly of MUC1-lipopeptide vaccine candidates is described. Chimeras consisting of MUC1 glycopeptides (bearing multiple copies of the TN and T tumour-associated carbohydrate antigens) tethered to the lipopeptide immunoadjuvant Pam3CysSer were synthesised in high yields using a fragment-based condensation strategy.

Original languageEnglish
Pages (from-to)6249-6251
Number of pages3
JournalChemical Communications
Issue number34
Publication statusPublished - 14 Sept 2010
Externally publishedYes


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