Temporal analysis of reassortment and molecular evolution of Cucumber mosaic virus: Extra clues from its segmented genome

Kazusato Ohshima; Kosuke Matsumoto; Ryosuke Yasaka; Mai Nishiyama; Kenta Soejima; Savas Korkmaz; Simon Y.W. Ho; Adrian J. Gibbs; Minoru Takeshita

doi:10.1016/j.virol.2015.09.024

Temporal analysis of reassortment and molecular evolution of Cucumber mosaic virus: Extra clues from its segmented genome

Kazusato Ohshima^*, Kosuke Matsumoto, Ryosuke Yasaka, Mai Nishiyama, Kenta Soejima, Savas Korkmaz, Simon Y.W. Ho, Adrian J. Gibbs, Minoru Takeshita

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

34 Citations (Scopus)

Abstract

Cucumber mosaic virus (CMV) is a damaging pathogen of over 200 mono- and dicotyledonous crop species worldwide. It has the broadest known host range of any virus, but the timescale of its evolution is unknown. To investigate the evolutionary history of this virus, we obtained the genomic sequences of 40 CMV isolates from brassicas sampled in Iran, Turkey and Japan, and combined them with published sequences. Our synonymous ('silent') site analyses revealed that the present CMV population is the progeny of a single ancestor existing 1550-2600 years ago, but that the population mostly radiated 295-545 years ago. We found that the major CMV lineages are not phylogeographically confined, but that recombination and reassortment is restricted to local populations and that no reassortant lineage is more than 251 years old. Our results highlight the different evolutionary patterns seen among viral pathogens of brassica crops across the world.

Original language	English
Pages (from-to)	188-197
Number of pages	10
Journal	Virology
Volume	487
DOIs	https://doi.org/10.1016/j.virol.2015.09.024
Publication status	Published - 1 Jan 2016

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10.1016/j.virol.2015.09.024

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@article{a48c131594a442b8b261068c94a29ae4,

title = "Temporal analysis of reassortment and molecular evolution of Cucumber mosaic virus: Extra clues from its segmented genome",

abstract = "Cucumber mosaic virus (CMV) is a damaging pathogen of over 200 mono- and dicotyledonous crop species worldwide. It has the broadest known host range of any virus, but the timescale of its evolution is unknown. To investigate the evolutionary history of this virus, we obtained the genomic sequences of 40 CMV isolates from brassicas sampled in Iran, Turkey and Japan, and combined them with published sequences. Our synonymous ('silent') site analyses revealed that the present CMV population is the progeny of a single ancestor existing 1550-2600 years ago, but that the population mostly radiated 295-545 years ago. We found that the major CMV lineages are not phylogeographically confined, but that recombination and reassortment is restricted to local populations and that no reassortant lineage is more than 251 years old. Our results highlight the different evolutionary patterns seen among viral pathogens of brassica crops across the world.",

keywords = "Cucumber mosaic virus, Cucumovirus, Evolution, Reassortment, Selection, Synonymous sites, Timescale",

author = "Kazusato Ohshima and Kosuke Matsumoto and Ryosuke Yasaka and Mai Nishiyama and Kenta Soejima and Savas Korkmaz and Ho, {Simon Y.W.} and Gibbs, {Adrian J.} and Minoru Takeshita",

note = "Publisher Copyright: {\textcopyright} 2015 Elsevier Inc..",

year = "2016",

month = jan,

day = "1",

doi = "10.1016/j.virol.2015.09.024",

language = "English",

volume = "487",

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journal = "Virology",

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T1 - Temporal analysis of reassortment and molecular evolution of Cucumber mosaic virus

T2 - Extra clues from its segmented genome

AU - Ohshima, Kazusato

AU - Matsumoto, Kosuke

AU - Yasaka, Ryosuke

AU - Nishiyama, Mai

AU - Soejima, Kenta

AU - Korkmaz, Savas

AU - Ho, Simon Y.W.

AU - Gibbs, Adrian J.

AU - Takeshita, Minoru

PY - 2016/1/1

Y1 - 2016/1/1

N2 - Cucumber mosaic virus (CMV) is a damaging pathogen of over 200 mono- and dicotyledonous crop species worldwide. It has the broadest known host range of any virus, but the timescale of its evolution is unknown. To investigate the evolutionary history of this virus, we obtained the genomic sequences of 40 CMV isolates from brassicas sampled in Iran, Turkey and Japan, and combined them with published sequences. Our synonymous ('silent') site analyses revealed that the present CMV population is the progeny of a single ancestor existing 1550-2600 years ago, but that the population mostly radiated 295-545 years ago. We found that the major CMV lineages are not phylogeographically confined, but that recombination and reassortment is restricted to local populations and that no reassortant lineage is more than 251 years old. Our results highlight the different evolutionary patterns seen among viral pathogens of brassica crops across the world.

AB - Cucumber mosaic virus (CMV) is a damaging pathogen of over 200 mono- and dicotyledonous crop species worldwide. It has the broadest known host range of any virus, but the timescale of its evolution is unknown. To investigate the evolutionary history of this virus, we obtained the genomic sequences of 40 CMV isolates from brassicas sampled in Iran, Turkey and Japan, and combined them with published sequences. Our synonymous ('silent') site analyses revealed that the present CMV population is the progeny of a single ancestor existing 1550-2600 years ago, but that the population mostly radiated 295-545 years ago. We found that the major CMV lineages are not phylogeographically confined, but that recombination and reassortment is restricted to local populations and that no reassortant lineage is more than 251 years old. Our results highlight the different evolutionary patterns seen among viral pathogens of brassica crops across the world.

KW - Cucumber mosaic virus

KW - Cucumovirus

KW - Evolution

KW - Reassortment

KW - Selection

KW - Synonymous sites

KW - Timescale

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U2 - 10.1016/j.virol.2015.09.024

DO - 10.1016/j.virol.2015.09.024

M3 - Article

SN - 0042-6822

VL - 487

SP - 188

EP - 197

JO - Virology

JF - Virology

ER -

Temporal analysis of reassortment and molecular evolution of Cucumber mosaic virus: Extra clues from its segmented genome

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