Testing for glaucoma with the spatial frequency doubling illusion

Ted Maddess*, Ivan Goldberg, Jeffrey Dobinson, Stephen Wine, Alan H. Welsh, Andrew C. James

*Corresponding author for this work

    Research output: Contribution to journalArticlepeer-review

    88 Citations (Scopus)


    We examined the performance of tests for glaucoma based on the spatial frequency doubling (FD) illusion. Contrast thresholds for seeing the FD illusion in four large visual field regions were measured from 340 subjects who were tested up to seven times over 2 years. Median sensitivities of 91% at specificities of 95% were obtained. Test-retest variability for the worst hemifield thresholds averaged 2.22 db±0.09 S.E. for all tested groups, and significant progression was observed for glaucoma suspects over the seven visits, indicating that tests based on the FD illusion can detect diffuse early glaucomatous loss. Copyright (C) 1999 Elsevier Science Ltd.

    Original languageEnglish
    Pages (from-to)4258-4273
    Number of pages16
    JournalVision Research
    Issue number25
    Publication statusPublished - Dec 1999


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