Tethered-bilayer lipid membranes as a support for membrane-active peptides

B. A. Cornell; G. Krishna; P. D. Osman; R. D. Pace; L. Wieczorek

doi:10.1042/BST0290613

Tethered-bilayer lipid membranes as a support for membrane-active peptides

B. A. Cornell^*
, G. Krishna
, P. D. Osman
, R. D. Pace
, L. Wieczorek

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

70 Citations (Scopus)

Abstract

An immunosensing device, comprising a lipid membrane incorporating ion channels tethered to the surface of a gold electrode, has been reported [Cornell, Braach-Maksvytis, King, Osman, Raguse, Wieczorek and Pace (1997) Nature (London) 387, 580-583]. The present article describes key steps in the assembly of the device and provides further evidence for its proposed sensing mechanism.

Original language	English
Pages (from-to)	613-617
Number of pages	5
Journal	Biochemical Society Transactions
Volume	29
Issue number	4
DOIs	https://doi.org/10.1042/BST0290613
Publication status	Published - 2001
Externally published	Yes

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10.1042/BST0290613

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title = "Tethered-bilayer lipid membranes as a support for membrane-active peptides",

abstract = "An immunosensing device, comprising a lipid membrane incorporating ion channels tethered to the surface of a gold electrode, has been reported [Cornell, Braach-Maksvytis, King, Osman, Raguse, Wieczorek and Pace (1997) Nature (London) 387, 580-583]. The present article describes key steps in the assembly of the device and provides further evidence for its proposed sensing mechanism.",

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AU - Cornell, B. A.

AU - Krishna, G.

AU - Osman, P. D.

AU - Pace, R. D.

AU - Wieczorek, L.

PY - 2001

Y1 - 2001

N2 - An immunosensing device, comprising a lipid membrane incorporating ion channels tethered to the surface of a gold electrode, has been reported [Cornell, Braach-Maksvytis, King, Osman, Raguse, Wieczorek and Pace (1997) Nature (London) 387, 580-583]. The present article describes key steps in the assembly of the device and provides further evidence for its proposed sensing mechanism.

AB - An immunosensing device, comprising a lipid membrane incorporating ion channels tethered to the surface of a gold electrode, has been reported [Cornell, Braach-Maksvytis, King, Osman, Raguse, Wieczorek and Pace (1997) Nature (London) 387, 580-583]. The present article describes key steps in the assembly of the device and provides further evidence for its proposed sensing mechanism.

KW - Ion channel biosensor

KW - Tethered membrane

UR - https://www.scopus.com/pages/publications/0034874625

U2 - 10.1042/BST0290613

DO - 10.1042/BST0290613

M3 - Article

SN - 0300-5127

VL - 29

SP - 613

EP - 617

JO - Biochemical Society Transactions

JF - Biochemical Society Transactions

IS - 4

ER -

Tethered-bilayer lipid membranes as a support for membrane-active peptides

Abstract

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