The Amphimedon queenslandica genome and the evolution of animal complexity

Mansi Srivastava; Oleg Simakov; Jarrod Chapman; Bryony Fahey; Marie E.A. Gauthier; Therese Mitros; Gemma S. Richards; Cecilia Conaco; Michael Dacre; Uffe Hellsten; Claire Larroux; Nicholas H. Putnam; Mario Stanke; Maja Adamska; Aaron Darling; Sandie M. Degnan; Todd H. Oakley; David C. Plachetzki; Yufeng Zhai; Marcin Adamski; Andrew Calcino; Scott F. Cummins; David M. Goodstein; Christina Harris; Daniel J. Jackson; Sally P. Leys; Shengqiang Shu; Ben J. Woodcroft; Michel Vervoort; Kenneth S. Kosik; Gerard Manning; Bernard M. Degnan; Daniel S. Rokhsar

doi:10.1038/nature09201

The Amphimedon queenslandica genome and the evolution of animal complexity

Mansi Srivastava^*, Oleg Simakov, Jarrod Chapman, Bryony Fahey, Marie E.A. Gauthier, Therese Mitros, Gemma S. Richards, Cecilia Conaco, Michael Dacre, Uffe Hellsten, Claire Larroux, Nicholas H. Putnam, Mario Stanke, Maja Adamska, Aaron Darling, Sandie M. Degnan, Todd H. Oakley, David C. Plachetzki, Yufeng Zhai, Marcin AdamskiAndrew Calcino, Scott F. Cummins, David M. Goodstein, Christina Harris, Daniel J. Jackson, Sally P. Leys, Shengqiang Shu, Ben J. Woodcroft, Michel Vervoort, Kenneth S. Kosik, Gerard Manning, Bernard M. Degnan, Daniel S. Rokhsar

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

822 Citations (Scopus)

Abstract

Sponges are an ancient group of animals that diverged from other metazoans over 600 million years ago. Here we present the draft genome sequence of Amphimedon queenslandica, a demosponge from the Great Barrier Reef, and show that it is remarkably similar to other animal genomes in content, structure and organization. Comparative analysis enabled by the sequencing of the sponge genome reveals genomic events linked to the origin and early evolution of animals, including the appearance, expansion and diversification of pan-metazoan transcription factor, signalling pathway and structural genes. This diverse ĝ€̃ toolkit'trade; of genes correlates with critical aspects of all metazoan body plans, and comprises cell cycle control and growth, development, somatic-and germ-cell specification, cell adhesion, innate immunity and allorecognition. Notably, many of the genes associated with the emergence of animals are also implicated in cancer, which arises from defects in basic processes associated with metazoan multicellularity.

Original language	English
Pages (from-to)	720-726
Number of pages	7
Journal	Nature
Volume	466
Issue number	7307
DOIs	https://doi.org/10.1038/nature09201
Publication status	Published - 5 Aug 2010
Externally published	Yes

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Srivastava, M., Simakov, O., Chapman, J., Fahey, B., Gauthier, M. E. A., Mitros, T., Richards, G. S., Conaco, C., Dacre, M., Hellsten, U., Larroux, C., Putnam, N. H., Stanke, M., Adamska, M., Darling, A., Degnan, S. M., Oakley, T. H., Plachetzki, D. C., Zhai, Y., ... Rokhsar, D. S. (2010). The Amphimedon queenslandica genome and the evolution of animal complexity. Nature, 466(7307), 720-726. https://doi.org/10.1038/nature09201

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title = "The Amphimedon queenslandica genome and the evolution of animal complexity",

abstract = "Sponges are an ancient group of animals that diverged from other metazoans over 600 million years ago. Here we present the draft genome sequence of Amphimedon queenslandica, a demosponge from the Great Barrier Reef, and show that it is remarkably similar to other animal genomes in content, structure and organization. Comparative analysis enabled by the sequencing of the sponge genome reveals genomic events linked to the origin and early evolution of animals, including the appearance, expansion and diversification of pan-metazoan transcription factor, signalling pathway and structural genes. This diverse ĝ{\~€} toolkit'trade; of genes correlates with critical aspects of all metazoan body plans, and comprises cell cycle control and growth, development, somatic-and germ-cell specification, cell adhesion, innate immunity and allorecognition. Notably, many of the genes associated with the emergence of animals are also implicated in cancer, which arises from defects in basic processes associated with metazoan multicellularity.",

author = "Mansi Srivastava and Oleg Simakov and Jarrod Chapman and Bryony Fahey and Gauthier, {Marie E.A.} and Therese Mitros and Richards, {Gemma S.} and Cecilia Conaco and Michael Dacre and Uffe Hellsten and Claire Larroux and Putnam, {Nicholas H.} and Mario Stanke and Maja Adamska and Aaron Darling and Degnan, {Sandie M.} and Oakley, {Todd H.} and Plachetzki, {David C.} and Yufeng Zhai and Marcin Adamski and Andrew Calcino and Cummins, {Scott F.} and Goodstein, {David M.} and Christina Harris and Jackson, {Daniel J.} and Leys, {Sally P.} and Shengqiang Shu and Woodcroft, {Ben J.} and Michel Vervoort and Kosik, {Kenneth S.} and Gerard Manning and Degnan, {Bernard M.} and Rokhsar, {Daniel S.}",

year = "2010",

month = aug,

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doi = "10.1038/nature09201",

language = "English",

volume = "466",

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Srivastava, M, Simakov, O, Chapman, J, Fahey, B, Gauthier, MEA, Mitros, T, Richards, GS, Conaco, C, Dacre, M, Hellsten, U, Larroux, C, Putnam, NH, Stanke, M, Adamska, M, Darling, A, Degnan, SM, Oakley, TH, Plachetzki, DC, Zhai, Y, Adamski, M, Calcino, A, Cummins, SF, Goodstein, DM, Harris, C, Jackson, DJ, Leys, SP, Shu, S, Woodcroft, BJ, Vervoort, M, Kosik, KS, Manning, G, Degnan, BM & Rokhsar, DS 2010, 'The Amphimedon queenslandica genome and the evolution of animal complexity', Nature, vol. 466, no. 7307, pp. 720-726. https://doi.org/10.1038/nature09201

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AU - Chapman, Jarrod

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AU - Gauthier, Marie E.A.

AU - Mitros, Therese

AU - Richards, Gemma S.

AU - Conaco, Cecilia

AU - Dacre, Michael

AU - Hellsten, Uffe

AU - Larroux, Claire

AU - Putnam, Nicholas H.

AU - Stanke, Mario

AU - Adamska, Maja

AU - Darling, Aaron

AU - Degnan, Sandie M.

AU - Oakley, Todd H.

AU - Plachetzki, David C.

AU - Zhai, Yufeng

AU - Adamski, Marcin

AU - Calcino, Andrew

AU - Cummins, Scott F.

AU - Goodstein, David M.

AU - Harris, Christina

AU - Jackson, Daniel J.

AU - Leys, Sally P.

AU - Shu, Shengqiang

AU - Woodcroft, Ben J.

AU - Vervoort, Michel

AU - Kosik, Kenneth S.

AU - Manning, Gerard

AU - Degnan, Bernard M.

AU - Rokhsar, Daniel S.

PY - 2010/8/5

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N2 - Sponges are an ancient group of animals that diverged from other metazoans over 600 million years ago. Here we present the draft genome sequence of Amphimedon queenslandica, a demosponge from the Great Barrier Reef, and show that it is remarkably similar to other animal genomes in content, structure and organization. Comparative analysis enabled by the sequencing of the sponge genome reveals genomic events linked to the origin and early evolution of animals, including the appearance, expansion and diversification of pan-metazoan transcription factor, signalling pathway and structural genes. This diverse ĝ€̃ toolkit'trade; of genes correlates with critical aspects of all metazoan body plans, and comprises cell cycle control and growth, development, somatic-and germ-cell specification, cell adhesion, innate immunity and allorecognition. Notably, many of the genes associated with the emergence of animals are also implicated in cancer, which arises from defects in basic processes associated with metazoan multicellularity.

AB - Sponges are an ancient group of animals that diverged from other metazoans over 600 million years ago. Here we present the draft genome sequence of Amphimedon queenslandica, a demosponge from the Great Barrier Reef, and show that it is remarkably similar to other animal genomes in content, structure and organization. Comparative analysis enabled by the sequencing of the sponge genome reveals genomic events linked to the origin and early evolution of animals, including the appearance, expansion and diversification of pan-metazoan transcription factor, signalling pathway and structural genes. This diverse ĝ€̃ toolkit'trade; of genes correlates with critical aspects of all metazoan body plans, and comprises cell cycle control and growth, development, somatic-and germ-cell specification, cell adhesion, innate immunity and allorecognition. Notably, many of the genes associated with the emergence of animals are also implicated in cancer, which arises from defects in basic processes associated with metazoan multicellularity.

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VL - 466

SP - 720

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JO - Nature

JF - Nature

IS - 7307

ER -

The Amphimedon queenslandica genome and the evolution of animal complexity

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