The chemical master equation with respect to reaction counts

Vikram Sunkara*

*Corresponding author for this work

    Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

    6 Citations (Scopus)

    Abstract

    It is well known that many realistic mathematical models of biological and chemical systems, such as enzyme cascades and gene regulatory networks, need to include stochasticity. These systems can be described as Markov processes and are modeled using the Chemical Master Equation (CME). The CME is a differential-difference equation (continuous in time and discrete in the state space) for the probability of certain state at a given time. The state space is the population count of species in the system. However we can also consider the CME with the state space given by the counts of the number of reactions occurring in the system. This form of CME is not frequently used in the literature. This paper, through new results, gives motivation towards considering computing the CME over the reaction counts rather than species counts.

    Original languageEnglish
    Title of host publication18th World IMACS Congress and MODSIM 2009 - International Congress on Modelling and Simulation
    Subtitle of host publicationInterfacing Modelling and Simulation with Mathematical and Computational Sciences, Proceedings
    EditorsR.S. Anderssen, R.D. Braddock, L.T.H. Newham
    PublisherModelling and Simulation Society of Australia and New Zealand Inc (MSSANZ)
    Pages703-707
    Number of pages5
    ISBN (Electronic)9780975840078
    Publication statusPublished - 1 Jan 2009
    Event18th World IMACS Congress and International Congress on Modelling and Simulation: Interfacing Modelling and Simulation with Mathematical and Computational Sciences, MODSIM 2009 - Cairns, Australia
    Duration: 13 Jul 200917 Jul 2009

    Publication series

    Name18th World IMACS Congress and MODSIM 2009 - International Congress on Modelling and Simulation: Interfacing Modelling and Simulation with Mathematical and Computational Sciences, Proceedings

    Conference

    Conference18th World IMACS Congress and International Congress on Modelling and Simulation: Interfacing Modelling and Simulation with Mathematical and Computational Sciences, MODSIM 2009
    Country/TerritoryAustralia
    CityCairns
    Period13/07/0917/07/09

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