The coatomer of Trypanosoma brucei

Alexander G. Maier, Helena Webb, Martina Ding, Martina Bremser, Mark Carrington, Christine Clayton*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

19 Citations (Scopus)

Abstract

Coatomer is a multisubunit complex involved in trafficking of vesicles between the endoplasmatic reticulum and the Golgi apparatus. From sequence homologies, all seven subunits, α-, β-, β′-, γ-, δ-, ε-, and ζ-COP, are encoded in the genome of Trypanosoma brucei. The complete predicted amino-acid sequences of β-, β′-, and ζ-COP show only 20-30% identity with higher eucaryotic homologues. The trypanosome coatomer complex was partially purified using a procedure similar to that used for bovine coatomer.

Original languageEnglish
Pages (from-to)55-61
Number of pages7
JournalMolecular and Biochemical Parasitology
Volume115
Issue number1
DOIs
Publication statusPublished - 2001
Externally publishedYes

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